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19

TNGX

🏥 Healthcare

Tango Therapeutics, Inc.

Conservative #1315Aggressive #1159High RiskModerate 65F↑ 17pt
$12.10-4.20%
Day High$12.60
Day Low$12.03
Volume0.8M
Mkt Cap$1.3B
52W Low $152W High $13
Market Cap
$1.3B
P/E Ratio
N/A
Rev Growth
15.2%
Sector avg: 161.5%
Earnings Growth
-28.1%
Profit Margin
-151.1%
Sector avg: -3292.7%
Debt/Equity
0.22

Why This Score

TNGX scores 19.3 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Risk Factors
  • Momentum reversion risk: Extreme momentum (523%) increases mean-reversion probability. 5-point penalty applied.
  • Procyclicality: Late-cycle macro signals reduce confidence in extreme-momentum names. 2-point additional penalty.
  • Signal divergence: Fundamental and ML signals disagree by a significant margin, reducing confidence.
  • Above-average volatility (40.2%) may not suit conservative risk tolerance.

Net penalties of -15.1 points significantly impact the ranking. Without these adjustments, TNGX would rank considerably higher.

Score Breakdown

Overall Score19.3
Fundamental Score38.5
ML Score11.0

Score by Horizon

3 Month
18.4
6 Month
20.6
Primary
1 Year
21.6

Quality Assessment

C
Earnings Grade
Mixed fundamentals, potential quality issues
Quality Flags
Pipeline concentration: $1.3B biotech/pharma — likely single-product revenue with binary risk
Speculative Classification
Speculative growth — negative margins and ROE with momentum-driven price action. High risk of mean reversion.
Speculative micro-cap — no earnings, sub-$2B market cap, momentum-driven. Position sizing should reflect elevated risk.
Conservative score reduced by 6 points.

Position Sizing

Suggested Allocation
2%
Confidence
high

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
100
Advancing
Sentiment (2.5%)
74
Positive
Analyst (6.4%)
75
Favorable
Tradability (post-hoc)
87
Grade A
Base
20.0
SHAP
+1.3
Factors
-0.1
Divergence
-1.9
Final
19.3
Positive adjustment
Negative adjustment
Base blend
Final score

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)47.0
Technical (Momentum, Weinstein, Volatility)76.0
External (Sentiment, Analyst, Macro)87.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage89%

Growth Estimates

Short-term
-14.7% to -8.6%
Medium-term
-19.9% to -11.1%
Long-term
-25.1% to -13.5%

ML Model Core Features100 trained inputs → ML Score: 11

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score75.0/100
Target Upside+18.1%
Coverage8 analysts
Market Sentiment
Sentiment Score74.3/100
News Volume1 articles
Technical Stage
Weinstein Stage2 — Advancing
12M Momentum+5.2%
6M Momentum+0.9%
Volatility+0.4%
Momentum & Technical
Momentum Acceleration+430.9%
Momentum ConsistencyWeak (0.18)
Relative Strength vs Sector+498.8%
Trend Strength (ADX Proxy)Strong (5.0)
Momentum Quality+4.249
Momentum BreadthBroad ✓
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
3%
Low risk
Sector RevGr Rank
P63
Revenue growth vs Healthcare peers
Sector PE Rank
P40
Valuation vs Healthcare peers
Sector FCF Rank
P20
Free cash flow vs Healthcare peers
Growth Deviation
+0.0σ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 52 relative to sector peers52/100
Machine learning model ranks this stock at the 34th percentileP34
ML model weight reduced to 9% due to macro conditions: market in extended rally phase; yield curve inverted (recession indicator); late-cycle economic indicators detected9% ML weight
SHAP feature alignment: +1.3pt (features align with model priorities)—
Blend: 91% fund (51.5) + 9% ML (33.1) + SHAP(+1.3) = 51.1—
Factor quality: -0.1pt (multi-factor composite)—
Momentum mean-reversion: -6.0pt (523% 12m momentum)—
Market cap adjustment: -8.0 points ($1.3B market cap)-8.0 pts
Divergence penalty: -1.0pt (fund 17pt higher)—
Risk Factors
Risk assessment: high. Annualized volatility 40.2%. Max drawdown 19% (-4.3 pts)High
Earnings quality grade C: mixed earnings quality, some red flags. Score adjusted by -17 pointsGrade C
Quality concern: Elevated non-operating income: 15pp gap between net and operating margin; High accrual ratio (-45.1%) — earnings quality concern; Pipeline concentration: $1.3B biotech/pharma — likely single-product revenue with binary riskFlag

Sector Peer Comparison(Healthcare — Rank #299 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
TNGX19.3N/A15.2%-151.1%$1.3B
INCY89.615.821.2%25.0%$20.1B
GMAB85.513.122.8%36.4%$18.5B
CPRX82.213.723.5%37.6%$3.0B
VRTX78.032.18.9%32.9%$126.0B
ASND75.716.698.0%-31.7%$13.3B
NBIX74.726.521.4%16.7%$12.5B
ALKS74.616.5-6.4%23.9%$5.5B
AMGN73.826.010.0%21.0%$199.0B
ARGX73.635.178.6%38.0%$50.9B
HOLX73.331.11.7%13.8%$16.8B
REGN72.719.41.0%31.4%$84.9B
ISRG72.361.720.5%28.4%$172.5B
EXEL71.915.17.0%33.7%$11.7B
KRYS71.041.4473.0%30.7%$8.0B
HALO70.216.822.4%43.7%$9.3B
Sector Average37.1252.3161.5%-3292.7%—

Market Sentimentvia FMP

Analyst Consensus
Buy8 analysts
Buy: 8
Price Target
$15consensus
Low $12Median $15High $19
+24.0% to consensus target

Company Overviewvia FMP

Tango Therapeutics, Inc., a biotechnology company, discovers and develops drugs for the treatment of cancer. Its lead program is TNG908, a synthetic lethal small molecule inhibitor of protein arginine methyltransferase 5 that is being developed as a treatment for cancers with methylthioadenosine phosphorylase deletions. The company also develops Ubiquitin-specific protease 1, an inhibitor to treat patients with BRCA1 or BRCA2-mutant cancers; and Target 3 for STK11-mutant cancers. Tango Therapeutics, Inc. has a strategic collaboration with Gilead Sciences, Inc. for the discovery, development, and commercialization of a pipeline of therapies for patients with cancer. The company was founded in 2017 and is based in Cambridge, Massachusetts.

CEO
Malte Peters
Employees
155
Beta
1.76
Industry
Biotechnology
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
52.0
Neutral
Trend
Bullish
10-day vs 50-day MA
From 52W High
-11.1%
High: $13.6
From 52W Low
+1074.3%
Low: $1.03
Moving Averages
10-Day
$12.60
Below
20-Day
$12.40
Below
50-Day
$11.10
Above
200-Day
$7.80
Above
60-Day Support
$8.3
60-Day Resistance
$13.6
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 2 — AdvancingScore: 90/100

Stock is in an uptrend above the 200-day moving average. This is the stage where institutional accumulation typically occurs. The 50-day SMA provides support.

Favorable technical position; 50-day SMA acts as support
Price vs 200 SMA
+55.1%
200 SMA Slope (60d)
+55.13%
Rising
Volume Ratio
0.85x
10d avg vs 50d avg
Days in Stage
100
Confidence: 90%

Financial Statementslast 4 quarters via FMP

MetricQ3 2025Q2 2025Q1 2025Q4 2024
Revenue$54M$3M$5M$4M
Gross Profit$53M$3M$5M$4M
Operating Income$14M$-41M$-43M$-41M
Net Income$16M$-39M$-40M$-38M
EPS (Diluted)$0.14$-0.35$-0.36$-0.34
Gross Margin99.0%80.4%100.0%100.0%
Operating Margin26.2%-1287.9%-788.8%-993.7%
Net Margin29.5%-1221.4%-739.5%-915.0%

Why This Stock

HealthcareRevenue growth 15.2%

Tradability FilterGrade A — 87/100Score impact: -27.9pt

Volume
100
2.9M avg/day
Dollar Vol
91
$36M/day
Float
84
60M shares
Mkt Cap
48
$1.3B
Range
100
1220% spread
Composite Liquidity Score87/100
FDCBA

Multi-Year Range Analysis

Sideways: 0/100
YearLowHighRangeStatus
2021$8.90$18.8471.7%Wide
2022$3.18$11.00110.3%Wide
2023$2.47$13.03136.3%Wide
2024$2.70$13.01131.3%Wide
2025$1.03$11.20166.3%Wide
3-Year Range
170.7%
Narrow Years
0 / 5
Sideways Penalty
None
Free Float
54.1%
Outstanding Shares
110M
Bid-Ask Spread
1220.0%
Institutional Tradable
Yes

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.