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70

HALO

🏥 Healthcare

Halozyme Therapeutics, Inc.

Conservative #98Aggressive #27Low RiskMixed 55ML↑ 22pt
$70.35-0.01%
Day High$70.70
Day Low$69.13
Volume1.2M
Mkt Cap$8.3B
52W Low $4852W High $82
Market Cap
$9.3B
P/E Ratio
16.8
Sector avg: 252.3
Rev Growth
22.4%
Sector avg: 161.5%
Earnings Growth
57.7%
Profit Margin
43.7%
Sector avg: -3292.7%
Debt/Equity
4.14

Why This Score

HALO scores 70.2 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Strengths
  • Strong profitability: ROE of 122.1% exceeds the 15% quality threshold.
  • High net margin of 43.7%, indicating pricing power and operational efficiency.
  • Positive but moderate momentum (34%) — steady appreciation without overheating.
  • ML model assigns a high-conviction signal (97/100), indicating strong pattern recognition across 82 features.
Risk Factors
  • Signal divergence: Fundamental and ML signals disagree by a significant margin, reducing confidence.
  • Above-average volatility (10.1%) may not suit conservative risk tolerance.
  • Elevated leverage (D/E 4.14) increases financial risk in a rising-rate environment.

Minor adjustments (-3.0 points) applied. HALO's rank of #98 primarily reflects its factor profile relative to the conservative weight vector.

Score Breakdown

Overall Score70.2
Fundamental Score62.2
ML Score97.0

Score by Horizon

3 Month
80.9
6 Month
90.5
Primary
1 Year
95.2

Quality Assessment

A
Earnings Grade
Strong fundamentals, high earnings quality
Quality Flags
Extreme leverage: D/E ratio of 4.1x — balance sheet risk

Position Sizing

Suggested Allocation
5%
Confidence
high

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
100
Advancing
Sentiment (2.5%)
60
Positive
Analyst (6.4%)
65
Favorable
Tradability (post-hoc)
96
Grade A
Base
69.2
SHAP
+2.3
Factors
+1.7
Divergence
-3.0
Final
70.2
Positive adjustment
Negative adjustment
Base blend
Final score

Factor Breakdown

66AVG
Value70
Quality95
Growth90
Stability35
Investment40

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)77.0
Technical (Momentum, Weinstein, Volatility)77.0
External (Sentiment, Analyst, Macro)81.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage96%

Growth Estimates

Short-term
+10.9% to +16.9%
Medium-term
+16.1% to +25.2%
Long-term
+24.0% to +36.5%

ML Model Core Features100 trained inputs → ML Score: 97

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score64.8/100
Target Upside+7.6%
Coverage27 analysts
Market Sentiment
Sentiment Score60.4/100
News Volume1 articles
Technical Stage
Weinstein Stage2 — Advancing
12M Momentum+0.3%
6M Momentum+0.1%
Volatility+0.1%
Momentum & Technical
Momentum Acceleration+25.7%
Momentum ConsistencyWeak (0.25)
Relative Strength vs Sector+9.9%
Trend Strength (ADX Proxy)Strong (3.4)
Momentum Quality+0.280
Momentum BreadthBroad ✓
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
7%
Low risk
Sector RevGr Rank
P72
Revenue growth vs Healthcare peers
Sector PE Rank
P29
Valuation vs Healthcare peers
Sector FCF Rank
P81
Free cash flow vs Healthcare peers
Growth Deviation
+0.0σ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 70 relative to sector peers70/100
Machine learning model ranks this stock at the 92th percentileP92
ML model weight reduced to 9% due to macro conditions: market in extended rally phase; yield curve inverted (recession indicator); late-cycle economic indicators detected9% ML weight
SHAP feature alignment: +2.4pt (features align with model priorities)—
Blend: 91% fund (70.0) + 9% ML (92.3) + SHAP(+2.4) = 74.4—
Factor quality: +1.8pt (multi-factor composite)—
Risk assessment: low. Annualized volatility 10.1%. Max drawdown 18% (-4.2 pts)Low
Market cap adjustment: +0.5 points ($9.3B market cap)+0.5 pts
Divergence penalty: -1.8pt (ML 22pt higher)—
Risk Factors
Earnings quality grade A: strong earnings quality and financial health. Score adjusted by -10 pointsGrade A
Quality concern: Extreme leverage: D/E ratio of 4.1x — balance sheet risk; R&D-adjusted ROIC: 21.0% (original: 31.4%). Biotechnology has ~40% R&D intensity. Capitalizing R&D over 5 years increases invested capital by ~100%.Flag

Sector Peer Comparison(Healthcare — Rank #15 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
HALO70.216.822.4%43.7%$9.3B
INCY89.615.821.2%25.0%$20.1B
GMAB85.513.122.8%36.4%$18.5B
CPRX82.213.723.5%37.6%$3.0B
VRTX78.032.18.9%32.9%$126.0B
ASND75.716.698.0%-31.7%$13.3B
NBIX74.726.521.4%16.7%$12.5B
ALKS74.616.5-6.4%23.9%$5.5B
AMGN73.826.010.0%21.0%$199.0B
ARGX73.635.178.6%38.0%$50.9B
HOLX73.331.11.7%13.8%$16.8B
REGN72.719.41.0%31.4%$84.9B
ISRG72.361.720.5%28.4%$172.5B
EXEL71.915.17.0%33.7%$11.7B
KRYS71.041.4473.0%30.7%$8.0B
BMRN69.722.318.0%15.0%$11.5B
Sector Average37.1252.3161.5%-3292.7%—

Market Sentimentvia FMP

Analyst Consensus
Buy27 analysts
Buy: 17Hold: 9Sell: 1
Price Target
$76consensus
Low $56Median $75High $94
+8.2% to consensus target

Company Overviewvia FMP

Halozyme Therapeutics, Inc. operates as a biopharma technology platform company in the United States, Switzerland, Ireland, Belgium, Japan, and internationally. The company's products are based on the ENHANZE drug delivery technology, a patented recombinant human hyaluronidase enzyme (rHuPH20) that enables the subcutaneous delivery of injectable biologics, such as monoclonal antibodies and other therapeutic molecules, as well as small molecules and fluids. Its flagship product is Hylenex recombinant, a formulation of rHuPH20 to facilitate subcutaneous fluid administration for achieving hydration to enhance the dispersion and absorption of other injected drugs in subcutaneous urography and to improve resorption of radiopaque agents. The company also develops Perjeta; RITUXAN HYCELA and MabThera SC for the treatment of non-Hodgkin lymphoma and chronic lymphocytic leukemia (CLL); RITUXAN SC for patients with CLL; and HYQVIA for the treatment of immunodeficiency disorders. In addition, it is developing Tecentriq for non-small cell lung cancer; OCREVUS for multiple sclerosis; DARZALEX for the treatment of patients with amyloidosis, smoldering myeloma, and multiple myeloma; nivolumab for the treatment of solid tumors; ARGX-113, a human neonatal Fc receptor; ARGX-117 to treat autoimmune diseases; and BMS-986179, an anti-CD-73 antibody. The company has collaborations with F. Hoffmann-La Roche, Ltd.; Hoffmann-La Roche, Inc.; Baxalta US Inc.; Baxalta GmbH; Pfizer Inc.; Janssen Biotech, Inc.; AbbVie, Inc.; Eli Lilly and Company; Bristol-Myers Squibb Company; Alexion Pharma Holding; ARGENX BVBA; Horizon Therapeutics plc; National Institute of Allergy and Infectious Diseases; Centre for the AIDS Programme of Research in South Africa; and ViiV Healthcare Limited for small and large molecule targets for the treatment and prevention of HIV. Halozyme Therapeutics, Inc. was founded in 1998 and is based in San Diego, California.

CEO
Helen I. Torley
Employees
350
Beta
0.98
Industry
Biotechnology
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
32.2
Neutral
Trend
Bullish
10-day vs 50-day MA
From 52W High
-14.4%
High: $82.22
From 52W Low
+48.1%
Low: $47.5
Moving Averages
10-Day
$74.40
Below
20-Day
$75.60
Below
50-Day
$71.90
Below
200-Day
$65.90
Above
60-Day Support
$61.23
60-Day Resistance
$82.22
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 2 — AdvancingScore: 57/100

Stock is in an uptrend above the 200-day moving average. This is the stage where institutional accumulation typically occurs. The 50-day SMA provides support.

Favorable technical position; 50-day SMA acts as support
Price vs 200 SMA
+6.8%
200 SMA Slope (60d)
+4.75%
Rising
Volume Ratio
1.15x
10d avg vs 50d avg
Days in Stage
49
Confidence: 90%
Recent Gap Down

Financial Statementslast 4 quarters via FMP

MetricQ4 2025Q3 2025Q2 2025Q1 2025
Revenue$452M$354M$326M$265M
Gross Profit$350M$299M$279M$216M
Operating Income$254M$218M$202M$142M
Net Income$-142M$175M$165M$118M
EPS (Diluted)$-1.20$1.43$1.33$0.93
Gross Margin77.4%84.4%85.8%81.7%
Operating Margin56.3%61.5%62.2%53.4%
Net Margin-31.3%49.5%50.7%44.6%

Why This Stock

HealthcareP/E ratio of 16.8Revenue growth 22.4%Profit margin 43.7%Earnings quality grade A

Tradability FilterGrade A — 96/100Score impact: -12.3pt

Volume
100
2.2M avg/day
Dollar Vol
100
$153M/day
Float
100
117M shares
Mkt Cap
76
$9.3B
Range
97
73% spread
Composite Liquidity Score96/100
FDCBA

Multi-Year Range Analysis

Sideways: 0/100
YearLowHighRangeStatus
2021$31.79$56.4055.8%Wide
2022$31.36$59.4661.9%Wide
2023$29.85$57.0062.5%Wide
2024$33.15$65.5365.6%Wide
2025$47.50$79.5050.4%Wide
3-Year Range
90.8%
Narrow Years
0 / 5
Sideways Penalty
None
Free Float
99.1%
Outstanding Shares
118M
Bid-Ask Spread
73.0%
Institutional Tradable
Yes

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.