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NRIX

๐Ÿฅ Healthcare

Nurix Therapeutics, Inc.

Conservative #1020Aggressive #611Moderate RiskModerate 64
$15.78-0.06%
Day High$16.04
Day Low$15.58
Volume0.1M
Mkt Cap$1.4B
52W Low $852W High $23
Market Cap
$1.4B
P/E Ratio
N/A
Rev Growth
54.0%
Sector avg: 161.5%
Earnings Growth
-36.6%
Profit Margin
-314.9%
Sector avg: -3292.7%
Debt/Equity
0.10

Why This Score

NRIX scores 33.7 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Risk Factors
  • Above-average volatility (18.5%) may not suit conservative risk tolerance.

Minor adjustments (-0.4 points) applied. NRIX's rank of #1020 primarily reflects its factor profile relative to the conservative weight vector.

Score Breakdown

Overall Score33.7
Fundamental Score32.0
ML Score38.0

Score by Horizon

3 Month
28.3
6 Month
31.6
Primary
1 Year
33.3

Quality Assessment

D
Earnings Grade
Weak fundamentals or significant quality concerns
Quality Flags
Pipeline concentration: $1.4B biotech/pharma โ€” likely single-product revenue with binary risk

Position Sizing

Suggested Allocation
4.3%
Confidence
high

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
100
Advancing
Sentiment (2.5%)
39
Negative
Analyst (6.4%)
50
Neutral
Tradability (post-hoc)
86
Grade A
Base
33.2
SHAP
+0.7
Factors
-0.2
Final
33.7
Positive adjustment
Negative adjustment
Base blend
Final score

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)49.0
Technical (Momentum, Weinstein, Volatility)74.0
External (Sentiment, Analyst, Macro)60.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage89%

Growth Estimates

Short-term
-6.6% to -1.8%
Medium-term
-9.1% to -2.1%
Long-term
-11.6% to -2.3%

ML Model Core Features100 trained inputs โ†’ ML Score: 38

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score50.0/100
Target Upside+0.0%
Coverage0 analysts
Market Sentiment
Sentiment Score39.1/100
News Volume0 articles
Technical Stage
Weinstein Stage2 โ€” Advancing
12M Momentum+0.0%
6M Momentum+0.7%
Volatility+0.2%
Momentum & Technical
Momentum Acceleration-66.0%
Momentum ConsistencyWeak (0.01)
Relative Strength vs Sector-23.4%
Trend Strength (ADX Proxy)Weak (0.1)
Momentum Quality+0.008
Momentum BreadthBroad โœ“
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
0%
Low risk
Sector RevGr Rank
P86
Revenue growth vs Healthcare peers
Sector PE Rank
P22
Valuation vs Healthcare peers
Sector FCF Rank
P9
Free cash flow vs Healthcare peers
Growth Deviation
+0.0ฯƒ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 51 relative to sector peers51/100
Machine learning model ranks this stock at the 41th percentileP41
ML model weight reduced to 9% due to macro conditions: market in extended rally phase; yield curve inverted (recession indicator); late-cycle economic indicators detected9% ML weight
SHAP feature alignment: +0.7pt (features align with model priorities)โ€”
Blend: 91% fund (51.2) + 9% ML (39.5) + SHAP(+0.7) = 50.9โ€”
Factor quality: -0.2pt (multi-factor composite)โ€”
Risk assessment: moderate. Annualized volatility 18.5%. Max drawdown 22% (-5.7 pts)Moderate
Market cap adjustment: -8.0 points ($1.4B market cap)-8.0 pts
Risk Factors
Earnings quality grade D: weak earnings quality, multiple concerns. Score adjusted by -23 pointsGrade D
Quality concern: Non-operating gain: net margin (-314.9%) exceeds operating margin (-340.2%) by 25pp โ€” likely one-time item; Pipeline concentration: $1.4B biotech/pharma โ€” likely single-product revenue with binary riskFlag

Sector Peer Comparison(Healthcare โ€” Rank #181 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
NRIX33.7N/A54.0%-314.9%$1.4B
INCY89.615.821.2%25.0%$19.6B
GMAB85.613.122.8%36.4%$17.9B
CPRX82.113.723.5%37.6%$3.0B
VRTX78.032.18.9%32.9%$121.8B
ASND75.816.698.0%-31.7%$13.8B
NBIX74.826.521.4%16.7%$13.1B
AMGN73.926.010.0%21.0%$204.8B
ARGX73.535.178.6%38.0%$47.4B
HOLX73.331.11.7%13.8%$16.8B
REGN72.419.41.0%31.4%$80.2B
ISRG72.261.720.5%28.4%$180.9B
EXEL71.615.17.0%33.7%$11.9B
ALKS71.516.5-6.4%23.9%$5.0B
KRYS71.041.4473.0%30.7%$7.9B
HALO70.316.822.4%43.7%$8.2B
Sector Average37.041.9161.5%-3292.7%โ€”

Market Sentimentvia FMP

Company Overviewvia FMP

Nurix Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of small molecule therapies for the treatment of cancer and immune disorders. The company develops NX-2127, an orally available Bruton's tyrosine kinase (BTK) degrader for the treatment of relapsed or refractory B-cell malignancies; NX-5948, an orally bioavailable BTK degrader for the treatment of relapsed or refractory B-cell malignancies and autoimmune diseases; and NX-1607, an orally available Casitas B-lineage lymphoma proto-oncogene-B (CBL-B) inhibitor for immuno-oncology indications. It also develops NX-0255, a CBL-B inhibitor for ex vivo use to enhance adoptive T-cell therapy; and DeTIL-0255 that is in the Phase 1 clinical trial for the treatment of gynecologic cancers, including ovarian, endometrial, and cervical cancer. The company has a strategic collaboration agreement with Gilead Sciences, Inc. for cancer and other challenging diseases patients; and Sanofi S.A. The company was formerly known as Nurix Inc. and changed its name to Nurix Therapeutics, Inc. in October 2018. The company was incorporated in 2009 and is headquartered in San Francisco, California.

CEO
Arthur T. Sands
Employees
286
Beta
1.97
Industry
Biotechnology
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
48.2
Neutral
Trend
Bearish
10-day vs 50-day MA
From 52W High
-29.8%
High: $22.5
From 52W Low
+93.2%
Low: $8.18
Moving Averages
10-Day
$15.70
Above
20-Day
$16.20
Below
50-Day
$17.70
Below
200-Day
$13.10
Above
60-Day Support
$15.06
60-Day Resistance
$22.5
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 2 โ€” AdvancingScore: 84/100

Stock is in an uptrend above the 200-day moving average. This is the stage where institutional accumulation typically occurs. The 50-day SMA provides support.

Favorable technical position; 50-day SMA acts as support
Price vs 200 SMA
+20.6%
200 SMA Slope (60d)
+13.56%
Rising
Volume Ratio
0.63x
10d avg vs 50d avg
Days in Stage
81
Confidence: 90%

Financial Statementslast 4 quarters via FMP

MetricQ4 2025Q3 2025Q2 2025Q1 2025
Revenue$14M$8M$44M$18M
Gross Profit$9M$3M$-34M$-51M
Operating Income$-83M$-91M$-48M$-63M
Net Income$-78M$-86M$-43M$-56M
EPS (Diluted)$-0.82$-1.03$-0.52$-0.67
Gross Margin65.9%36.7%-77.3%-277.5%
Operating Margin-612.0%-1157.7%-109.7%-340.7%
Net Margin-576.1%-1094.8%-98.7%-305.4%

Why This Stock

HealthcareRevenue growth 54.0%

Tradability FilterGrade A โ€” 86/100Score impact: -20.1pt

Volume
100
1.5M avg/day
Dollar Vol
82
$22M/day
Float
95
87M shares
Mkt Cap
47
$1.4B
Range
100
175% spread
Composite Liquidity Score86/100
FDCBA

Multi-Year Range Analysis

Sideways: 0/100
YearLowHighRangeStatus
2021$21.53$47.8475.9%Wide
2022$7.52$30.52120.9%Wide
2023$4.22$13.99107.3%Wide
2024$7.65$29.56117.8%Wide
2025$8.18$22.5093.4%Wide
3-Year Range
150%
Narrow Years
0 / 5
Sideways Penalty
None
Free Float
99.9%
Outstanding Shares
87M
Bid-Ask Spread
175.0%
Institutional Tradable
Yes

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.