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46

MIRM

๐Ÿฅ Healthcare

Mirum Pharmaceuticals, Inc.

Conservative #718Aggressive #32Low RiskMixed 51MLโ†‘ 24pt
$93.27-14.13%
Day High$100.19
Day Low$90.26
Volume1.7M
Mkt Cap$4.8B
52W Low $3752W High $107
Market Cap
$4.8B
P/E Ratio
N/A
Rev Growth
80.8%
Sector avg: 161.5%
Earnings Growth
46.2%
Profit Margin
-26.1%
Sector avg: -3292.7%
Debt/Equity
1.41

Why This Score

MIRM scores 46.5 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Risk Factors
  • Momentum reversion risk: Extreme momentum (117%) increases mean-reversion probability. 3-point penalty applied.
  • Signal divergence: Fundamental and ML signals disagree by a significant margin, reducing confidence.
  • Above-average volatility (14.2%) may not suit conservative risk tolerance.
  • Elevated leverage (D/E 1.41) increases financial risk in a rising-rate environment.

Moderate penalties (-8.3 points) reflect identified risk factors. The overall score balances these against the stock's fundamental strengths.

Score Breakdown

Overall Score46.5
Fundamental Score44.7
ML Score75.0

Score by Horizon

3 Month
69.7
6 Month
77.9
Primary
1 Year
82.0

Quality Assessment

A
Earnings Grade
Strong fundamentals, high earnings quality
Speculative Classification
Speculative growth โ€” negative margins and ROE with momentum-driven price action. High risk of mean reversion.
Conservative score reduced by 3 points.

Position Sizing

Suggested Allocation
5%
Confidence
high

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
100
Advancing
Sentiment (2.5%)
70
Positive
Analyst (6.4%)
77
Favorable
Tradability (post-hoc)
87
Grade A
Base
44.8
SHAP
+2.6
Factors
+1.4
Divergence
-2.3
Final
46.5
Positive adjustment
Negative adjustment
Base blend
Final score

Factor Breakdown

60AVG
Value40
Quality40
Growth90
Stability60
Investment70

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)43.0
Technical (Momentum, Weinstein, Volatility)91.0
External (Sentiment, Analyst, Macro)87.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage96%

Growth Estimates

Short-term
+9.7% to +15.8%
Medium-term
+14.7% to +23.9%
Long-term
+22.0% to +34.8%

ML Model Core Features100 trained inputs โ†’ ML Score: 75

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score76.6/100
Target Upside+5.7%
Coverage16 analysts
Market Sentiment
Sentiment Score70.3/100
News Volume1 articles
Technical Stage
Weinstein Stage2 โ€” Advancing
12M Momentum+1.2%
6M Momentum+0.4%
Volatility+0.1%
Momentum & Technical
Momentum Acceleration+77.2%
Momentum ConsistencyModerate (0.34)
Relative Strength vs Sector+92.3%
Trend Strength (ADX Proxy)Strong (5.0)
Momentum Quality+1.126
Momentum BreadthBroad โœ“
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
1%
Low risk
Sector RevGr Rank
P90
Revenue growth vs Healthcare peers
Sector PE Rank
P22
Valuation vs Healthcare peers
Sector FCF Rank
P61
Free cash flow vs Healthcare peers
Growth Deviation
+0.1ฯƒ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 58 relative to sector peers58/100
Machine learning model ranks this stock at the 82th percentileP82
ML model weight reduced to 9% due to macro conditions: market in extended rally phase; yield curve inverted (recession indicator); late-cycle economic indicators detected9% ML weight
SHAP feature alignment: +3.7pt (features align with model priorities)โ€”
Blend: 91% fund (57.9) + 9% ML (82.2) + SHAP(+3.7) = 63.8โ€”
Factor quality: +2.0pt (multi-factor composite)โ€”
Risk assessment: low. Annualized volatility 14.2%Low
Momentum mean-reversion: -1.8pt (117% 12m momentum)โ€”
Market cap adjustment: +0.5 points ($6.2B market cap)+0.5 pts
Divergence penalty: -2.1pt (ML 24pt higher)โ€”
Risk Factors

No risk factors identified.

Sector Peer Comparison(Healthcare โ€” Rank #102 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
MIRM46.5N/A80.8%-26.1%$4.8B
INCY89.915.821.2%25.0%$19.6B
GMAB86.113.122.8%36.4%$17.9B
CPRX83.713.723.5%37.6%$3.0B
EXEL78.315.17.0%33.7%$11.9B
ASND78.216.698.0%-31.7%$13.8B
VRTX78.232.18.9%32.9%$121.8B
NBIX75.126.521.4%16.7%$13.1B
RPRX75.025.15.1%32.4%$19.3B
HOLX74.831.11.7%13.8%$16.8B
AMGN74.226.010.0%21.0%$204.8B
ARGX73.735.178.6%38.0%$47.4B
REGN73.019.41.0%31.4%$80.2B
ALKS72.916.5-6.4%23.9%$5.0B
ISRG72.761.720.5%28.4%$180.9B
KRYS71.541.4473.0%30.7%$7.9B
Sector Average36.441.9161.5%-3292.7%โ€”

Company Overviewvia FMP

Mirum Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies for debilitating rare and orphan diseases. The company's lead product candidate is LIVMARLI, an investigational oral drug for the treatment of progressive familial intrahepatic cholestasis disease, as well as for the treatment of Alagille syndrome and biliary atresia disease. It also develops Volixibat drug for treatment of intrahepatic cholestasis of pregnancy and primary sclerosing cholangitis. Mirum Pharmaceuticals, Inc. was incorporated in 2018 and is headquartered in Foster City, California.

CEO
Christopher Peetz
Employees
334
Beta
0.50
Industry
Biotechnology
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
40.3
Neutral
Trend
Bullish
10-day vs 50-day MA
From 52W High
-15.4%
High: $109.28
From 52W Low
+150.7%
Low: $36.88
Moving Averages
10-Day
$103.80
Below
20-Day
$102.90
Below
50-Day
$91.40
Above
200-Day
$69.60
Above
60-Day Support
$63.23
60-Day Resistance
$109.28
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 2 โ€” AdvancingScore: 80/100

Stock is in an uptrend above the 200-day moving average. This is the stage where institutional accumulation typically occurs. The 50-day SMA provides support.

Favorable technical position; 50-day SMA acts as support
Price vs 200 SMA
+32.8%
200 SMA Slope (60d)
+22.75%
Rising
Volume Ratio
0.88x
10d avg vs 50d avg
Days in Stage
100
Confidence: 90%
Recent Gap Down

Financial Statementslast 4 quarters via FMP

MetricQ4 2025Q3 2025Q2 2025Q1 2025
Revenue$149M$133M$128M$112M
Gross Profit$193M$107M$104M$89M
Operating Income$-5M$3M$-5M$-15M
Net Income$-6M$3M$-6M$-15M
EPS (Diluted)$-0.12$0.05$-0.12$-0.30
Gross Margin129.5%80.8%81.7%79.4%
Operating Margin-3.1%2.0%-3.9%-13.6%
Net Margin-3.8%2.2%-4.6%-13.2%

Why This Stock

HealthcareRevenue growth 80.8%

Tradability FilterGrade A โ€” 87/100Score impact: +0.4pt

Volume
90
757K avg/day
Dollar Vol
100
$80M/day
Float
75
45M shares
Mkt Cap
69
$4.8B
Range
100
191% spread
Composite Liquidity Score87/100
FDCBA

Multi-Year Range Analysis

Sideways: 0/100
YearLowHighRangeStatus
2021$12.82$21.5050.6%Wide
2022$14.63$30.5570.5%Wide
2023$18.46$35.5663.3%Wide
2024$23.14$48.8971.5%Wide
2025$36.88$82.5876.5%Wide
3-Year Range
126.9%
Narrow Years
0 / 5
Sideways Penalty
None
Free Float
86.5%
Outstanding Shares
52M
Bid-Ask Spread
191.0%
Institutional Tradable
Yes

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.