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50

BBIO

🏥 Healthcare

BridgeBio Pharma, Inc.

Conservative #561Aggressive #822Low RiskMixed 57
$66.54-2.59%
Day High$71.50
Day Low$63.53
Volume5.4M
Mkt Cap$12.8B
52W Low $2852W High $85
Market Cap
$13.1B
P/E Ratio
N/A
Rev Growth
2285.3%
Sector avg: 161.5%
Earnings Growth
16.7%
Profit Margin
-225.3%
Sector avg: -3292.7%
Debt/Equity
N/A

Why This Score

BBIO scores 50.3 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Strengths
  • Strong profitability: ROE of 46.6% exceeds the 15% quality threshold.
  • Minimal leverage (D/E -0.96) provides financial flexibility and downside protection.
Risk Factors
  • Signal divergence: Fundamental and ML signals disagree by a significant margin, reducing confidence.

Moderate penalties (-6.1 points) reflect identified risk factors. The overall score balances these against the stock's fundamental strengths.

Score Breakdown

Overall Score50.3
Fundamental Score63.7
ML Score8.0

Score by Horizon

3 Month
39.9
6 Month
44.5
Primary
1 Year
46.9

Quality Assessment

F
Earnings Grade
Weak fundamentals or significant quality concerns
Quality Flags
Negative ROIC (-77.5%) with high ROE (46.6%) — capital structure distortion (possibly negative equity or one-time gain)

Position Sizing

Suggested Allocation
5%
Confidence
medium

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
100
Advancing
Sentiment (2.5%)
84
Positive
Analyst (6.4%)
74
Favorable
Tradability (post-hoc)
97
Grade A
Base
52.6
SHAP
+3.1
Factors
+0.7
Divergence
-6.1
Final
50.3
Positive adjustment
Negative adjustment
Base blend
Final score

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)79.0
Technical (Momentum, Weinstein, Volatility)91.0
External (Sentiment, Analyst, Macro)89.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage89%

Growth Estimates

Short-term
-4.0% to +0.3%
Medium-term
-6.0% to +0.5%
Long-term
-8.0% to +0.6%

ML Model Core Features100 trained inputs → ML Score: 8

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score74.0/100
Target Upside+43.8%
Coverage25 analysts
Market Sentiment
Sentiment Score83.5/100
News Volume1 articles
Technical Stage
Weinstein Stage2 — Advancing
12M Momentum+1.2%
6M Momentum+0.5%
Volatility+0.1%
Momentum & Technical
Momentum Acceleration+70.2%
Momentum ConsistencyModerate (0.39)
Relative Strength vs Sector+91.2%
Trend Strength (ADX Proxy)Strong (5.0)
Momentum Quality+1.032
Momentum BreadthBroad ✓
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
0%
Low risk
Sector RevGr Rank
P99
Revenue growth vs Healthcare peers
Sector PE Rank
P40
Valuation vs Healthcare peers
Sector FCF Rank
P38
Free cash flow vs Healthcare peers
Growth Deviation
+1.6σ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 55 relative to sector peers55/100
Machine learning model ranks this stock at the 49th percentileP49
ML model weight reduced to 9% due to macro conditions: market in extended rally phase; yield curve inverted (recession indicator); late-cycle economic indicators detected9% ML weight
SHAP feature alignment: +3.1pt (features align with model priorities)
Blend: 91% fund (55.4) + 9% ML (46.2) + SHAP(+3.1) = 57.7
Factor quality: +0.7pt (multi-factor composite)
Risk assessment: low. Annualized volatility 10.0%. Max drawdown 11% (-1.1 pts)Low
Momentum mean-reversion: -1.8pt (116% 12m momentum)
Market cap adjustment: +2.0 points ($13.1B market cap)+2.0 pts
Risk Factors
Earnings quality grade F: assessed. Score adjusted by -29 pointsGrade F
Quality concern: Non-operating loss: operating margin (-172.4%) exceeds net margin (-225.3%) by 53pp — possible write-down; Negative ROIC (-77.5%) with high ROE (46.6%) — capital structure distortion (possibly negative equity or one-time gain); High accrual ratio (27.2%) — earnings quality concernFlag

Sector Peer Comparison(Healthcare — Rank #75 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
BBIO50.3N/A2285.3%-225.3%$13.1B
INCY89.615.821.2%25.0%$20.1B
GMAB85.513.122.8%36.4%$18.5B
CPRX82.213.723.5%37.6%$3.0B
VRTX78.032.18.9%32.9%$126.0B
ASND75.716.698.0%-31.7%$13.3B
NBIX74.726.521.4%16.7%$12.5B
ALKS74.616.5-6.4%23.9%$5.5B
AMGN73.826.010.0%21.0%$199.0B
ARGX73.635.178.6%38.0%$50.9B
HOLX73.331.11.7%13.8%$16.8B
REGN72.719.41.0%31.4%$84.9B
ISRG72.361.720.5%28.4%$172.5B
EXEL71.915.17.0%33.7%$11.7B
KRYS71.041.4473.0%30.7%$8.0B
HALO70.216.822.4%43.7%$9.3B
Sector Average37.1252.3161.5%-3292.7%

Market Sentimentvia FMP

Analyst Consensus
Buy26 analysts
Buy: 25Hold: 1
Price Target
$99consensus
Low $83Median $96High $157
+48.7% to consensus target

Company Overviewvia FMP

BridgeBio Pharma, Inc. engages in the discovery, development, and delivery of various medicines for genetic diseases. The company has a pipeline of 30 development programs that include product candidates ranging from early discovery to late-stage development. Its products in development programs include AG10 and BBP-265, a small molecule stabilizer of transthyretin, or TTR that is in Phase 3 clinical trial for the treatment of TTR amyloidosis-cardiomyopathy, or ATTR-CM; BBP-831, a small molecule selective FGFR1-3 inhibitor, which is Phase 2 clinical trial to treat achondroplasia in pediatric patients; and BBP-631, an AAV5 gene transfer product candidate that is in Phase 2 clinical trial for the treatment of congenital adrenal hyperplasia, or CAH, driven by 21-hydroxylase deficiency, or 21OHD. The company also develops Encaleret, a small molecule antagonist of the calcium sensing receptor, or CaSR, which is in phase 2 proof-of-concept clinical trial for Autosomal Dominant Hypocalcemia Type 1, or ADH1; and BBP-711 for the treatment of hyperoxaluria, as well as patients suffering from recurrent kidney stones. In addition, it engages in developing products for Mendelian, oncology, and gene therapy diseases. BridgeBio Pharma, Inc. has license and collaboration agreements with the Leland Stanford Junior University; and The Regents of the University of California; Leidos Biomedical Research, Inc. The company was founded in 2015 and is headquartered in Palo Alto, California.

CEO
Neil Kumar
Employees
725
Beta
1.10
Industry
Biotechnology
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
37.8
Neutral
Trend
Bearish
10-day vs 50-day MA
From 52W High
-21.7%
High: $84.94
From 52W Low
+134.9%
Low: $28.33
Moving Averages
10-Day
$71.60
Below
20-Day
$72.90
Below
50-Day
$74.90
Below
200-Day
$57.00
Above
60-Day Support
$62.84
60-Day Resistance
$84.94
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 2 — AdvancingScore: 88/100

Stock is in an uptrend above the 200-day moving average. This is the stage where institutional accumulation typically occurs. The 50-day SMA provides support.

Favorable technical position; 50-day SMA acts as support
Price vs 200 SMA
+16.7%
200 SMA Slope (60d)
+26.82%
Rising
Volume Ratio
1.36x
10d avg vs 50d avg
Days in Stage
100
Confidence: 90%
Breakout Volume ConfirmedRecent Gap Up

Financial Statementslast 4 quarters via FMP

MetricQ4 2025Q3 2025Q2 2025Q1 2025
Revenue$154M$121M$111M$117M
Gross Profit$139M$114M$107M$114M
Operating Income$-185M$-145M$-134M$-104M
Net Income$-197M$-183M$-182M$-167M
EPS (Diluted)$-1.00$-0.96$-0.95$-0.88
Gross Margin90.0%94.6%96.7%97.7%
Operating Margin-120.1%-120.3%-121.4%-89.5%
Net Margin-127.9%-151.4%-164.5%-143.5%

Why This Stock

HealthcareRevenue growth 2285.3%

Tradability FilterGrade A — 97/100Score impact: -2.1pt

Volume
100
2.7M avg/day
Dollar Vol
100
$182M/day
Float
100
154M shares
Mkt Cap
82
$13.1B
Range
100
200% spread
Composite Liquidity Score97/100
FDCBA

Multi-Year Range Analysis

Sideways: 0/100
YearLowHighRangeStatus
2021$11.20$72.97146.8%Wide
2022$4.98$18.13113.8%Wide
2023$7.10$44.32144.8%Wide
2024$21.62$41.0462%Wide
2025$27.53$78.4496.1%Wide
3-Year Range
166.8%
Narrow Years
0 / 5
Sideways Penalty
None
Free Float
79.9%
Outstanding Shares
193M
Bid-Ask Spread
200.0%
Institutional Tradable
Yes

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.