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ZLAB

πŸ₯ Healthcare

Zai Lab Limited

Conservative #1308Aggressive #1047High RiskHigh 83
$19.39+0.10%
Day High$19.50
Day Low$19.05
Volume0.6M
Mkt Cap$2.1B
52W Low $1652W High $44
Market Cap
$2.2B
P/E Ratio
N/A
Rev Growth
49.6%
Sector avg: 161.5%
Earnings Growth
23.2%
Profit Margin
-46.8%
Sector avg: -3292.7%
Debt/Equity
0.29

Why This Score

ZLAB scores 20.9 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Strengths
  • High conviction (83/100) β€” fundamental and ML signals agree on this stock.
Risk Factors
  • Above-average volatility (13.5%) may not suit conservative risk tolerance.

Net penalties of -12.0 points significantly impact the ranking. Without these adjustments, ZLAB would rank considerably higher.

Score Breakdown

Overall Score20.9
Fundamental Score27.6
ML Score34.0

Score by Horizon

3 Month
43.9
6 Month
49.0
Primary
1 Year
51.6

Quality Assessment

A
Earnings Grade
Strong fundamentals, high earnings quality
Quality Flags
Pipeline concentration: $2.2B biotech/pharma β€” likely single-product revenue with binary risk
Country Risk:
Score penalty of points applied for domicile risk

Position Sizing

Suggested Allocation
5%
Confidence
high

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
0
Declining
Sentiment (2.5%)
58
Neutral
Analyst (6.4%)
71
Favorable
Tradability (post-hoc)
86
Grade A
Base
16.9
SHAP
+1.8
Factors
+0.7
Conviction
+1.5
Final
20.9
Positive adjustment
Negative adjustment
Base blend
Final score

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)63.0
Technical (Momentum, Weinstein, Volatility)28.0
External (Sentiment, Analyst, Macro)82.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage89%

Growth Estimates

Short-term
-3.4% to +0.8%
Medium-term
-4.8% to +1.5%
Long-term
-6.2% to +2.1%

ML Model Core Features100 trained inputs β†’ ML Score: 34

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score70.5/100
Target Upside+76.7%
Coverage11 analysts
Market Sentiment
Sentiment Score58.2/100
News Volume1 articles
Technical Stage
Weinstein Stage4 β€” Declining
12M Momentum-0.4%
6M Momentum-0.4%
Volatility+0.1%
Momentum & Technical
Momentum Acceleration-2.7%
Momentum ConsistencyStrong (0.94)
Relative Strength vs Sector-66.6%
Trend Strength (ADX Proxy)Strong (3.1)
Momentum Quality-0.185
Momentum BreadthNarrow
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
2%
Low risk
Sector RevGr Rank
P83
Revenue growth vs Healthcare peers
Sector PE Rank
P40
Valuation vs Healthcare peers
Sector FCF Rank
P23
Free cash flow vs Healthcare peers
Growth Deviation
+0.0Οƒ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 62 relative to sector peers62/100
Machine learning model ranks this stock at the 53th percentileP53
ML model weight reduced to 9% due to macro conditions: market in extended rally phase; yield curve inverted (recession indicator); late-cycle economic indicators detected9% ML weight
SHAP feature alignment: +1.8pt (features align with model priorities)β€”
Blend: 91% fund (61.6) + 9% ML (51.6) + SHAP(+1.8) = 62.5β€”
Factor quality: +0.7pt (multi-factor composite)β€”
Market cap adjustment: -4.0 points ($2.2B market cap)-4.0 pts
Conviction bonus: +1.6pt (conviction=83)β€”
Risk Factors
Risk assessment: high. Annualized volatility 13.5%. Max drawdown 56% (-12.0 pts). Price momentum -42% (-7.4 pts)High
Country risk: China -14.0pt [structural: -8pt, macro: -6.0pt] (VIE structure risk, HFCAA delisting risk, regulatory seizure precedent)Country
Earnings quality grade A: strong earnings quality and financial health. Score adjusted by -7 pointsGrade A
Quality concern: Pipeline concentration: $2.2B biotech/pharma β€” likely single-product revenue with binary riskFlag

Sector Peer Comparison(Healthcare β€” Rank #292 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
ZLAB20.9N/A49.6%-46.8%$2.2B
INCY89.615.821.2%25.0%$20.1B
GMAB85.513.122.8%36.4%$18.5B
CPRX82.213.723.5%37.6%$3.0B
VRTX78.032.18.9%32.9%$126.0B
ASND75.716.698.0%-31.7%$13.3B
NBIX74.726.521.4%16.7%$12.5B
ALKS74.616.5-6.4%23.9%$5.5B
AMGN73.826.010.0%21.0%$199.0B
ARGX73.635.178.6%38.0%$50.9B
HOLX73.331.11.7%13.8%$16.8B
REGN72.719.41.0%31.4%$84.9B
ISRG72.361.720.5%28.4%$172.5B
EXEL71.915.17.0%33.7%$11.7B
KRYS71.041.4473.0%30.7%$8.0B
HALO70.216.822.4%43.7%$9.3B
Sector Average37.1252.3161.5%-3292.7%β€”

Market Sentimentvia FMP

Analyst Consensus
Buy11 analysts
Buy: 9Hold: 2
Price Target
$35consensus
Low $35Median $35High $35
+80.5% to consensus target

Company Overviewvia FMP

Zai Lab Limited develops and commercializes therapies to treat oncology, autoimmune disorders, infectious diseases, and neuroscience primarily in Mainland China and Hong Kong. The company's commercial products include Zejula, a once-daily small-molecule poly polymerase 1/2 inhibitor; Optune, a device that delivers tumor treating fields; NUZYRA for acute bacterial skin and skin structure infections, and community acquired bacterial pneumonia; and Qinlock to treat gastrointestinal stromal tumors. It also develops Odronextamab to treat follicular lymphoma, diffuse large B-cell lymphoma, and other B-celllymphomas; Repotrectinib, a tyrosine kinase inhibitor (TKI) to target ROS1 and TRK A/B/C in TKI-naΓ―ve- or -pretreated cancer patients; Margetuximab for the treatment of breast and gastroesophageal cancers; Adagrasib for treating KRAS-G12C-mutated NSCLC, colorectal cancer, pancreatic cancer, and other solid tumors; and Bemarituzumab to treat gastric and gastroesophageal junction cancer. In addition, the company develops CLN-081 for the treatment of patients with EGFR exon 20 insertion NSCLC; Elzovantinib, an orally bioavailable multi-targeted kinase inhibitor; Tebotelimab, a tetravalent IgG4 monoclonal antibody; Retifanlimab that inhibits interactions between PD-1 and its ligands; ZL-2309, an orally active, selective, and ATP-competitive cell division cycle 7 (CDC7) kinase inhibitor; ZL-1201, a humanized IgG4 monoclonal antibody; Efgartigimod to reduce disease-causing immunoglobulin G antibodies; ZL-1102, a human nanobody targeting interleukin- 17A; KarXT for the treatment of psychiatric and neurological conditions; ZL-2313, an investigational inhibitor of triple-mutant EGFR harboring; ZL-2314, an investigational inhibitor of double-mutant EGFR harboring; and Sulbactam/durlobactam for the treatment of serious infections caused by Acinetobacter. Zai Lab Limited was incorporated in 2013 and is headquartered in Shanghai, China.

CEO
Ying Du
Employees
1,869
Beta
0.89
Industry
Biotechnology
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
71.3
Overbought
Trend
Bullish
10-day vs 50-day MA
From 52W High
-56.3%
High: $44.34
From 52W Low
+21.5%
Low: $15.96
Moving Averages
10-Day
$19.70
Below
20-Day
$18.50
Above
50-Day
$18.30
Above
200-Day
$27.90
Below
60-Day Support
$15.96
60-Day Resistance
$20.47
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 4 β€” DecliningScore: 10/100

Stock is in a downtrend below the 200-day moving average. Price is below both the 50-day and 200-day SMAs, indicating sustained selling pressure.

Unfavorable technical position; wait for Stage 1 basing
Price vs 200 SMA
-30.5%
200 SMA Slope (60d)
-13.45%
Falling
Volume Ratio
0.65x
10d avg vs 50d avg
Days in Stage
94
Confidence: 90%
Recent Gap Up

Financial Statementslast 4 quarters via FMP

MetricQ3 2025Q2 2025Q1 2025Q4 2024
Revenue$116M$110M$106M$109M
Gross Profit$69M$67M$68M$67M
Operating Income$-49M$-55M$-56M$-68M
Net Income$-36M$-41M$-48M$-82M
EPS (Diluted)$-0.33$-0.37$-0.45$-0.80
Gross Margin59.6%60.7%63.7%61.4%
Operating Margin-42.1%-49.9%-52.9%-62.2%
Net Margin-31.0%-37.0%-45.5%-74.9%

Why This Stock

HealthcareRevenue growth 49.6%

Tradability FilterGrade A β€” 86/100Score impact: -29.9pt

Volume
94
846K avg/day
Dollar Vol
73
$17M/day
Float
100
110M shares
Mkt Cap
60
$2.2B
Range
100
178% spread
Composite Liquidity Score86/100
FDCBA

Growth Projection Adjustment

0.7x dampening
weinstein basing

Growth estimates have been dampened based on technical and fundamental signals. This is a post-hoc adjustment to prevent overly optimistic projections for stocks showing declining momentum or deteriorating fundamentals.

Free Float
99.5%
Outstanding Shares
111M
Bid-Ask Spread
178.0%
Institutional Tradable
Yes

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.