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61

RIGL

๐Ÿฅ Healthcare

Rigel Pharmaceuticals, Inc.

Conservative #324Aggressive #46High Risk
$35.71+3.15%
Day High$36.66
Day Low$34.13
Volume0.3M
Mkt Cap$648M
52W Low $1652W High $52
Market Cap
$626M
P/E Ratio
5.6
Sector avg: 41.9
Rev Growth
53.4%
Sector avg: 161.5%
Earnings Growth
169.7%
Profit Margin
40.2%
Sector avg: -3292.7%
Debt/Equity
0.52

Why This Score

RIGL scores 61.2 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Strengths
  • Strong profitability: ROE of 204.7% exceeds the 15% quality threshold.
  • High net margin of 40.2%, indicating pricing power and operational efficiency.
  • Attractively valued at 5.6x earnings, below the market average.
  • High conviction (93/100) โ€” fundamental and ML signals agree on this stock.
Risk Factors
  • Liquidity concern: Limited trading volume or float results in a 2-point penalty for execution risk.
  • Signal divergence: Fundamental and ML signals disagree by a significant margin, reducing confidence.
  • Above-average volatility (31.9%) may not suit conservative risk tolerance.

Moderate penalties (-3.7 points) reflect identified risk factors. The overall score balances these against the stock's fundamental strengths.

Score Breakdown

Overall Score61.2
Fundamental Score55.6
ML Score82.0

Score by Horizon

3 Month
75.2
6 Month
84.0
Primary
1 Year
88.4

Quality Assessment

B
Quality Grade
Good quality โ€” solid metrics, minor concerns possible
1 quality flag detected โ€” see details below. These penalties are already factored into the final score.
Quality Flags
Pipeline concentration: $0.6B biotech/pharma โ€” likely single-product revenue with binary risk

Position Sizing

Suggested Allocation
2.5%
Confidence
high

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
100
Advancing
Sentiment (2.5%)
69
Positive
Analyst (6.4%)
63
Favorable
Tradability (post-hoc)
64
Grade Blow float
Base
58.9
SHAP
+1.2
Factors
+0.9
Conviction
+1.9
Divergence
-1.7
Final
61.2
Positive adjustment
Negative adjustment
Base blend
Final score

Factor Breakdown

81AVG
Value73
Quality100
Growth100
Stability51
Investment83

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)96.0
Technical (Momentum, Weinstein, Volatility)46.0
External (Sentiment, Analyst, Macro)83.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage89%

Growth Estimates

Short-term
-5.2% to +1.2%
Medium-term
-7.8% to +1.8%
Long-term
-10.4% to +2.4%

ML Model Core Features100 trained inputs โ†’ ML Score: 82

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score63.3/100
Target Upside+17.5%
Coverage15 analysts
Market Sentiment
Sentiment Score69.0/100
News Volume1 articles
Technical Stage
Weinstein Stage2 โ€” Advancing
12M Momentum+0.5%
6M Momentum-0.1%
Volatility+0.3%
Momentum & Technical
Momentum Acceleration+60.5%
Momentum ConsistencyDivergent (-0.24)
Relative Strength vs Sector+24.4%
Trend Strength (ADX Proxy)Moderate (1.5)
Momentum Quality+0.332
Momentum BreadthNarrow
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
14%
Low risk
Sector RevGr Rank
P85
Revenue growth vs Healthcare peers
Sector PE Rank
P98
Valuation vs Healthcare peers
Sector FCF Rank
P93
Free cash flow vs Healthcare peers
Growth Deviation
+0.0ฯƒ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 56 relative to sector peers56/100
Machine learning ensemble ranks this stock at the 82th percentileP82
Blended score: 80% fundamental (56) + 20% ML (82) = 60.960.9
Risk assessment: low. Low vol 0.3%; Drawdown 32% โ†’ 0.0ptLow
Earnings quality grade B: adequate earnings quality with minor concerns. Score adjusted by 0 pointsGrade B
SHAP feature alignment: +1.2pt (features align with model priorities)SHAP
Conviction adj: +1.9pt (conviction=N/A)Conviction
Divergence penalty: -1.7pt (ML 26pt higher)Divergence
Risk Factors
Quality concern: Pipeline concentration: $0.6B biotech/pharma โ€” likely single-product revenue with binary riskFlag
Liquidity penalty: -2.0pt (grade B)Liquidity

Sector Peer Comparison(Healthcare โ€” Rank #40 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
RIGL61.25.653.4%40.2%$626M
INCY89.915.821.2%25.0%$19.6B
GMAB86.113.122.8%36.4%$17.9B
CPRX83.713.723.5%37.6%$3.0B
ASND78.316.698.0%-31.7%$13.8B
EXEL78.315.17.0%33.7%$11.9B
VRTX78.232.18.9%32.9%$121.8B
NBIX75.126.521.4%16.7%$13.1B
RPRX75.025.15.1%32.4%$19.3B
HOLX74.831.11.7%13.8%$16.8B
AMGN74.226.010.0%21.0%$204.8B
ARGX73.735.178.6%38.0%$47.4B
REGN73.019.41.0%31.4%$80.2B
ALKS72.916.5-6.4%23.9%$5.0B
ISRG72.761.720.5%28.4%$180.9B
KRYS71.541.4473.0%30.7%$7.9B
Sector Average36.641.9161.5%-3292.7%โ€”

Market Sentimentvia FMP

Analyst Consensus
Buy15 analysts
Buy: 8Hold: 7
Price Target
$40consensus
Low $38Median $40High $42
+12.0% to consensus target

Company Overviewvia FMP

Rigel Pharmaceuticals, Inc., a biotechnology company, discovers and develops small molecule drugs to treat hematologic disorders, cancer, and rare immune diseases. The company offers Tavalisse, an oral spleen tyrosine kinase inhibitor for the treatment of adult patients with chronic immune thrombocytopenia. It also develops Fostamatinib that is in phase III clinical trial for the treatment of warm autoimmune hemolytic anemia; phase III clinical trial for the treatment of hospitalized COVID-19 patients; and phase III clinical trial for the treatment of COVID-19. In addition, the company is developing R289, an oral interleukin receptor associated kinase 1/4 inhibitor, which is in phase I clinical trial for autoimmune, inflammatory, and hematology-oncology diseases; and R552, a receptor-interacting serine/threonine-protein kinase 1 inhibitor that has completed phase I clinical trial for autoimmune and inflammatory diseases. It has research and license agreements with AstraZeneca AB for the development and commercialization of R256, an inhaled JAK inhibitor; BerGenBio AS for the development and commercialization of AXL inhibitors in oncology; and Daiichi Sankyo to develop murine double minute 2 inhibitors for solid and hematological malignancies, as well as license and supply agreement with Kissei Pharmaceutical Co., Ltd. to develop and commercialize Fostamatinib. The company also has a license agreement and strategic collaboration with Eli Lilly and Company to co-develop and commercialize R552 for various indications, including autoimmune and inflammatory diseases, as well as other non-central nervous system (non-CNS) disease development candidates. Rigel Pharmaceuticals, Inc. was incorporated in 1996 and is headquartered in South San Francisco, California.

CEO
Raul R. Rodriguez
Employees
162
Beta
1.09
Industry
Biotechnology
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
64.3
Neutral
Trend
Bearish
10-day vs 50-day MA
From 52W High
-31.6%
High: $52.24
From 52W Low
+130.4%
Low: $15.5
Moving Averages
10-Day
$35.10
Above
20-Day
$35.00
Above
50-Day
$38.50
Below
200-Day
$32.00
Above
60-Day Support
$33.05
60-Day Resistance
$50.27
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 2 โ€” AdvancingScore: 78/100

Stock is in an uptrend above the 200-day moving average. This is the stage where institutional accumulation typically occurs. The 50-day SMA provides support.

Favorable technical position; 50-day SMA acts as support
Price vs 200 SMA
+11.6%
200 SMA Slope (60d)
+23.32%
Rising
Volume Ratio
0.7x
10d avg vs 50d avg
Days in Stage
100
Confidence: 90%

Financial Statementslast 4 quarters via FMP

MetricQ3 2025Q2 2025Q1 2025Q4 2024
Revenue$69M$102M$53M$58M
Gross Profit$65M$97M$49M$52M
Operating Income$28M$61M$13M$17M
Net Income$28M$60M$11M$14M
EPS (Diluted)$1.46$3.28$0.63$0.80
Gross Margin93.2%95.6%91.7%89.9%
Operating Margin40.9%60.1%23.9%28.9%
Net Margin40.2%58.6%21.5%24.9%

Why This Stock

HealthcareP/E ratio of 5.6Revenue growth 53.4%Profit margin 40.2%Earnings quality grade BValuation below sector median (P/E 5.6)

Tradability FilterGrade B โ€” 64/100Score impact: -4.3pt

Volume
76
455K avg/day
Dollar Vol
71
$16M/day
Float
42
18M shares
Mkt Cap
32
$626M
Range
100
237% spread
Composite Liquidity Score64/100
FDCBA
low float

Growth Projection Adjustment

0.15x dampening
weinstein declining

Growth estimates have been dampened based on technical and fundamental signals. This is a post-hoc adjustment to prevent overly optimistic projections for stocks showing declining momentum or deteriorating fundamentals.

Free Float
97.6%
Outstanding Shares
18M
Bid-Ask Spread
237.0%
Institutional Tradable
Yes

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.