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19

RGNX

๐Ÿฅ Healthcare

REGENXBIO Inc.

Conservative #1291Aggressive #1182Moderate RiskHigh 97
$8.75+2.58%
Day High$8.76
Day Low$8.24
Volume0.9M
Mkt Cap$443M
52W Low $552W High $16
Market Cap
$412M
P/E Ratio
N/A
Rev Growth
-7.7%
Sector avg: 161.5%
Earnings Growth
13.8%
Profit Margin
-110.3%
Sector avg: -3292.7%
Debt/Equity
1.66

Why This Score

RGNX scores 19.2 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Strengths
  • Positive but moderate momentum (22%) โ€” steady appreciation without overheating.
  • High conviction (97/100) โ€” fundamental and ML signals agree on this stock.
Risk Factors
  • Liquidity concern: Limited trading volume or float results in a 2-point penalty for execution risk.
  • Above-average volatility (17.8%) may not suit conservative risk tolerance.
  • Elevated leverage (D/E 1.66) increases financial risk in a rising-rate environment.

Minor adjustments (-2.0 points) applied. RGNX's rank of #1291 primarily reflects its factor profile relative to the conservative weight vector.

Score Breakdown

Overall Score19.2
Fundamental Score20.3
ML Score5.0

Score by Horizon

3 Month
33.8
6 Month
37.8
Primary
1 Year
39.8

Quality Assessment

F
Quality Grade
Low quality โ€” significant fundamental weaknesses
1 quality flag detected โ€” see details below. These penalties are already factored into the final score.
Quality Flags
Pipeline concentration: $0.4B biotech/pharma โ€” likely single-product revenue with binary risk

Position Sizing

Suggested Allocation
4.5%
Confidence
high

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
0
Declining
Sentiment (2.5%)
76
Positive
Analyst (6.4%)
68
Favorable
Tradability (post-hoc)
69
Grade Bsmall cap
Base
15.3
SHAP
+1.4
Conviction
+2.6
Divergence
-0.1
Final
19.2
Positive adjustment
Negative adjustment
Base blend
Final score

Factor Breakdown

31AVG
Value50
Quality0
Growth43
Stability46
Investment16

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)43.0
Technical (Momentum, Weinstein, Volatility)41.0
External (Sentiment, Analyst, Macro)86.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage89%

Growth Estimates

Short-term
-15.7% to -6.8%
Medium-term
-20.7% to -8.1%
Long-term
-25.8% to -9.3%

ML Model Core Features100 trained inputs โ†’ ML Score: 5

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score67.5/100
Target Upside+245.4%
Coverage20 analysts
Market Sentiment
Sentiment Score76.4/100
News Volume1 articles
Technical Stage
Weinstein Stage4 โ€” Declining
12M Momentum+0.2%
6M Momentum-0.1%
Volatility+0.2%
Momentum & Technical
Momentum Acceleration+32.1%
Momentum ConsistencyDivergent (-0.49)
Relative Strength vs Sector-2.8%
Trend Strength (ADX Proxy)Weak (1.2)
Momentum Quality+0.120
Momentum BreadthNarrow
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
1%
Low risk
Sector RevGr Rank
P11
Revenue growth vs Healthcare peers
Sector PE Rank
P22
Valuation vs Healthcare peers
Sector FCF Rank
P5
Free cash flow vs Healthcare peers
Growth Deviation
-0.0ฯƒ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 20 relative to sector peers20/100
Machine learning ensemble ranks this stock at the 5th percentileP5
Blended score: 80% fundamental (20) + 20% ML (5) = 17.217.2
Risk assessment: low. Low vol 0.2%; Drawdown 45% โ†’ 0.0ptLow
Earnings quality grade F: quality flags triggered โ€” see details below. Score adjusted by 0 pointsGrade F
SHAP feature alignment: +1.4pt (features align with model priorities)SHAP
Conviction adj: +2.6pt (conviction=N/A)Conviction
Divergence penalty: -0.1pt (ML 15pt lower)Divergence
Risk Factors
Quality concern: Pipeline concentration: $0.4B biotech/pharma โ€” likely single-product revenue with binary riskFlag
Liquidity penalty: -2.0pt (grade B)Liquidity

Sector Peer Comparison(Healthcare โ€” Rank #283 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
RGNX19.2N/A-7.7%-110.3%$412M
INCY89.915.821.2%25.0%$19.6B
GMAB86.113.122.8%36.4%$17.9B
CPRX83.713.723.5%37.6%$3.0B
ASND78.316.698.0%-31.7%$13.8B
EXEL78.315.17.0%33.7%$11.9B
VRTX78.232.18.9%32.9%$121.8B
NBIX75.126.521.4%16.7%$13.1B
RPRX75.025.15.1%32.4%$19.3B
HOLX74.831.11.7%13.8%$16.8B
AMGN74.226.010.0%21.0%$204.8B
ARGX73.735.178.6%38.0%$47.4B
REGN73.019.41.0%31.4%$80.2B
ALKS72.916.5-6.4%23.9%$5.0B
ISRG72.761.720.5%28.4%$180.9B
KRYS71.541.4473.0%30.7%$7.9B
Sector Average36.641.9161.5%-3292.7%โ€”

Company Overviewvia FMP

REGENXBIO Inc., a clinical-stage biotechnology company, provides gene therapy product candidates to deliver genes to cells to address genetic defects or to enable cells in the body to produce therapeutic proteins or antibodies that are intended to impact disease. Its gene therapy product candidates are based on NAV Technology Platform, a proprietary adeno-associated virus gene delivery platform. The company's lead product candidate is RGX-314, which is in Phase III clinical trial for the treatment of wet age-related macular degeneration. It is also developing RGX-121 that is in Phase I/II clinical trial to treat mucopolysaccharidosis type II;RGX-111, which is in Phase I/II clinical trial for treating mucopolysaccharidosis type I;RGX-181 which is in pre clinic stage for the treatment of late-infantile neuronal ceroid lipofuscinosis type II disease;RGX-202, to treat Duchenne muscular dystrophy which is in phase I/II clinical trial; and RGX-381, to treat the ocular manifestations of CLN2 disease which is in preclinical stage. REGENXBIO Inc. also licenses its NAV Technology Platform to other biotechnology and pharmaceutical companies; and has a collaboration and license agreement with Neurimmune AG to develop novel gene therapies. REGENXBIO Inc. was founded in 2008 and is headquartered in Rockville, Maryland.

CEO
Curran Simpson
Employees
353
Beta
1.05
Industry
Biotechnology
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
32.8
Neutral
Trend
Bearish
10-day vs 50-day MA
From 52W High
-46%
High: $16.19
From 52W Low
+73.6%
Low: $5.04
Moving Averages
10-Day
$8.20
Above
20-Day
$9.30
Below
50-Day
$12.20
Below
200-Day
$10.60
Below
60-Day Support
$7.61
60-Day Resistance
$16.19
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 4 โ€” DecliningScore: 26/100

Stock is in a downtrend below the 200-day moving average. Price is below both the 50-day and 200-day SMAs, indicating sustained selling pressure.

Unfavorable technical position; wait for Stage 1 basing
Transition signal: 3โ†’4
Price vs 200 SMA
-17.5%
200 SMA Slope (60d)
+16.68%
Rising
Volume Ratio
0.85x
10d avg vs 50d avg
Days in Stage
15
Confidence: 50%

Financial Statementslast 4 quarters via FMP

MetricQ3 2025Q2 2025Q1 2025Q4 2024
Revenue$30M$21M$89M$21M
Gross Profit$-32M$12M$86M$15M
Operating Income$-52M$-63M$12M$-51M
Net Income$-62M$-71M$6M$-51M
EPS (Diluted)$-1.20$-1.38$0.12$-1.01
Gross Margin-107.9%57.3%96.1%70.2%
Operating Margin-176.3%-296.3%13.6%-242.1%
Net Margin-208.3%-331.8%6.8%-241.3%

Why This Stock

Healthcare

Tradability FilterGrade B โ€” 69/100Score impact: -14.7pt

Volume
95
881K avg/day
Dollar Vol
54
$7M/day
Float
72
42M shares
Mkt Cap
20
$412M
Range
100
222% spread
Composite Liquidity Score69/100
FDCBA
small cap

Growth Projection Adjustment

0.08x dampening
weinstein decliningrevenue decline

Growth estimates have been dampened based on technical and fundamental signals. This is a post-hoc adjustment to prevent overly optimistic projections for stocks showing declining momentum or deteriorating fundamentals.

Free Float
82.4%
Outstanding Shares
51M
Bid-Ask Spread
222.0%
Institutional Tradable
Yes

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.