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NBTX

๐Ÿฅ Healthcare

Nanobiotix S.A.

Conservative #1388Aggressive #1452Moderate RiskLow 3Fโ†‘ 41pt
$27.10+5.04%
Day High$27.18
Day Low$25.89
Volume0.0M
Mkt Cap$1.3B
52W Low $352W High $30
Market Cap
$1.2B
P/E Ratio
N/A
Rev Growth
-132.1%
Sector avg: 161.5%
Earnings Growth
-71.6%
Profit Margin
-899.7%
Sector avg: -3292.7%
Debt/Equity
N/A

Why This Score

NBTX scores 9.6 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Strengths
  • Strong profitability: ROE of 76.7% exceeds the 15% quality threshold.
  • Minimal leverage (D/E -0.74) provides financial flexibility and downside protection.
Risk Factors
  • Momentum reversion risk: Extreme momentum (622%) increases mean-reversion probability. 5-point penalty applied.
  • Procyclicality: Late-cycle macro signals reduce confidence in extreme-momentum names. 2-point additional penalty.
  • Liquidity concern: Limited trading volume or float results in a 25-point penalty for execution risk.
  • Signal divergence: Fundamental and ML signals disagree by a significant margin, reducing confidence.
  • Above-average volatility (31.0%) may not suit conservative risk tolerance.

Net penalties of -53.2 points significantly impact the ranking. Without these adjustments, NBTX would rank considerably higher.

Score Breakdown

Overall Score9.6
Fundamental Score62.4
ML Score25.0

Score by Horizon

3 Month
4.4
6 Month
4.9
Primary
1 Year
5.2

Quality Assessment

D
Earnings Grade
Weak fundamentals or significant quality concerns
Quality Flags
Pipeline concentration: $1.2B biotech/pharma โ€” likely single-product revenue with binary risk
Speculative Classification
Anomalous margin data โ€” extreme values suggest one-time events or accounting irregularities.
Speculative micro-cap โ€” no earnings, sub-$2B market cap, momentum-driven. Position sizing should reflect elevated risk.
Conservative score reduced by 7 points.

Position Sizing

Suggested Allocation
2.6%
Confidence
high

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
100
Advancing
Sentiment (2.5%)
70
Positive
Analyst (6.4%)
75
Favorable
Tradability (post-hoc)
0
Grade Fvery low volume, very low dollar volume
Base
15.9
SHAP
+2.5
Factors
-0.9
Conviction
-4.5
Divergence
-3.4
Final
9.6
Positive adjustment
Negative adjustment
Base blend
Final score

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)50.0
Technical (Momentum, Weinstein, Volatility)84.0
External (Sentiment, Analyst, Macro)86.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage89%

Growth Estimates

Short-term
-36.4% to -24.4%
Medium-term
-50.1% to -34.1%
Long-term
-64.7% to -40.7%

ML Model Core Features100 trained inputs โ†’ ML Score: 25

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score75.0/100
Target Upside+5.4%
Coverage2 analysts
Market Sentiment
Sentiment Score69.5/100
News Volume1 articles
Technical Stage
Weinstein Stage2 โ€” Advancing
12M Momentum+6.2%
6M Momentum+1.8%
Volatility+0.3%
Momentum & Technical
Momentum Acceleration+438.6%
Momentum ConsistencyWeak (0.29)
Relative Strength vs Sector+597.5%
Trend Strength (ADX Proxy)Strong (5.0)
Momentum Quality+5.649
Momentum BreadthBroad โœ“
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
10%
Low risk
Sector RevGr Rank
P0
Revenue growth vs Healthcare peers
Sector PE Rank
P22
Valuation vs Healthcare peers
Sector FCF Rank
P44
Free cash flow vs Healthcare peers
Growth Deviation
-0.1ฯƒ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 60 relative to sector peers60/100
Machine learning model ranks this stock at the 19th percentileP19
ML model weight reduced to 9% due to macro conditions: market in extended rally phase; yield curve inverted (recession indicator); late-cycle economic indicators detected9% ML weight
SHAP feature alignment: +2.5pt (features align with model priorities)โ€”
Blend: 91% fund (60.3) + 9% ML (18.1) + SHAP(+2.5) = 59.0โ€”
Factor quality: -0.9pt (multi-factor composite)โ€”
Risk assessment: moderate. Annualized volatility 31.0%. Max drawdown 9% (-0.5 pts)Moderate
Momentum mean-reversion: -6.0pt (622% 12m momentum)โ€”
Market cap adjustment: -8.0 points ($1.2B market cap)-8.0 pts
Conviction penalty: -4.5pt (conviction=3)โ€”
Divergence penalty: -4.7pt (fund 41pt higher)โ€”
Risk Factors
Earnings quality grade D: weak earnings quality, multiple concerns. Score adjusted by -22 pointsGrade D
Quality concern: Non-operating loss: operating margin (-765.4%) exceeds net margin (-899.7%) by 134pp โ€” possible write-down; High accrual ratio (39.7%) โ€” earnings quality concern; Pipeline concentration: $1.2B biotech/pharma โ€” likely single-product revenue with binary riskFlag

Sector Peer Comparison(Healthcare โ€” Rank #326 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
NBTX9.6N/A-132.1%-899.7%$1.2B
INCY89.615.821.2%25.0%$19.6B
GMAB85.613.122.8%36.4%$17.9B
CPRX82.113.723.5%37.6%$3.0B
VRTX78.032.18.9%32.9%$121.8B
ASND75.816.698.0%-31.7%$13.8B
NBIX74.826.521.4%16.7%$13.1B
AMGN73.926.010.0%21.0%$204.8B
ARGX73.535.178.6%38.0%$47.4B
HOLX73.331.11.7%13.8%$16.8B
REGN72.419.41.0%31.4%$80.2B
ISRG72.261.720.5%28.4%$180.9B
EXEL71.615.17.0%33.7%$11.9B
ALKS71.516.5-6.4%23.9%$5.0B
KRYS71.041.4473.0%30.7%$7.9B
HALO70.316.822.4%43.7%$8.2B
Sector Average37.041.9161.5%-3292.7%โ€”

Market Sentimentvia FMP

Analyst Consensus
Buy2 analysts
Buy: 2
Price Target
$26consensus
Low $26Median $26High $26
-4.1% to consensus target

Company Overviewvia FMP

Nanobiotix S.A., a clinical-stage biotechnology, focuses on developing product candidates for the treatment of cancer. Its lead product candidate is NBTXR3, a sterile aqueous suspension of crystalline hafnium oxide nanoparticles used for the treatment of soft tissue sarcoma, head and neck cancers, liver cancers, prostate cancer, pancreatic cancer, esophageal cancer, rectal cancer, and non-small cell lung cancer. Nanobiotix S.A. has a partnership with LianBio to develop and commercialize NBTXR3 in Greater China, South Korea, Singapore, and Thailand. The company was incorporated in 2003 and is headquartered in Paris, France.

CEO
Laurent Levy
Employees
108
Beta
0.41
Industry
Biotechnology
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
70.1
Overbought
Trend
Bullish
10-day vs 50-day MA
From 52W High
-10.7%
High: $30.35
From 52W Low
+818.6%
Low: $2.95
Moving Averages
10-Day
$25.70
Above
20-Day
$24.00
Above
50-Day
$22.60
Above
200-Day
$14.70
Above
60-Day Support
$19.61
60-Day Resistance
$27.37
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 2 โ€” AdvancingScore: 75/100

Stock is in an uptrend above the 200-day moving average. This is the stage where institutional accumulation typically occurs. The 50-day SMA provides support.

Favorable technical position; 50-day SMA acts as support
Price vs 200 SMA
+84.4%
200 SMA Slope (60d)
+63.02%
Rising
Volume Ratio
0.82x
10d avg vs 50d avg
Days in Stage
100
Confidence: 90%
Key Reversal Detected (2026-02-19)

Financial Statementslast 4 quarters via FMP

MetricQ2 2025Q4 2024Q2 2024Q4 2023
Revenue$27M$-21M$9M$33M
Gross Profit$27M$-21M$9M$33M
Operating Income$808,000$-45M$-24M$-1M
Net Income$-5M$-46M$-22M$-12M
EPS (Diluted)$-0.11$-0.98$-0.46$-0.31
Gross Margin100.0%N/A100.0%100.0%
Operating Margin3.0%N/A-254.6%-4.3%
Net Margin-20.2%N/A-235.5%-35.2%

Why This Stock

Healthcare

Tradability FilterGrade F โ€” 0/100Score impact: -40.9pt

Low Tradability Warning

This stock has limited trading volume and/or float. Institutional investors may face difficulty entering or exiting positions without significant price impact. A post-hoc penalty has been applied to the composite score (this is not a backtested model factor โ€” it is a practical tradability overlay).

Volume
0
34K avg/day
Dollar Vol
0
$838K/day
Float
0
0K shares
Mkt Cap
0
$1.2B
Range
0
929% spread
Composite Liquidity Score0/100
FDCBA
very low volumevery low dollar volume

Multi-Year Range Analysis

Sideways: 0/100
YearLowHighRangeStatus
2021$6.51$18.0093.8%Wide
2022$2.32$10.42127.2%Wide
2023$1.75$11.00145.1%Wide
2024$2.76$8.96105.8%Wide
2025$2.82$30.35166%Wide
3-Year Range
178.2%
Narrow Years
0 / 5
Sideways Penalty
None

Growth Projection Adjustment

0.3x dampening
severe revenue decline

Growth estimates have been dampened based on technical and fundamental signals. This is a post-hoc adjustment to prevent overly optimistic projections for stocks showing declining momentum or deteriorating fundamentals.

Free Float
0.0%
Outstanding Shares
0M
Bid-Ask Spread
929.0%
Institutional Tradable
No

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.