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43

GLUE

๐Ÿฅ Healthcare

Monte Rosa Therapeutics, Inc.

Conservative #808Aggressive #822Moderate Risk
$18.50+2.27%
Day High$18.70
Day Low$17.59
Volume0.7M
Mkt Cap$1.2B
52W Low $452W High $26
Market Cap
$1.2B
P/E Ratio
74.7
Sector avg: 41.9
Rev Growth
0.0%
Sector avg: 161.5%
Earnings Growth
46.3%
Profit Margin
11.5%
Sector avg: -3292.7%
Debt/Equity
0.16

Why This Score

GLUE scores 43.5 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Strengths
  • High conviction (95/100) โ€” fundamental and ML signals agree on this stock.
Risk Factors
  • Momentum reversion risk: Extreme momentum (226%) increases mean-reversion probability. 5-point penalty applied.
  • Signal divergence: Fundamental and ML signals disagree by a significant margin, reducing confidence.
  • Elevated valuation at 74.7x earnings โ€” requires sustained growth to justify the premium.
  • Above-average volatility (26.9%) may not suit conservative risk tolerance.

Moderate penalties (-7.9 points) reflect identified risk factors. The overall score balances these against the stock's fundamental strengths.

Score Breakdown

Overall Score43.5
Fundamental Score54.4
ML Score20.0

Score by Horizon

3 Month
58.9
6 Month
65.8
Primary
1 Year
69.3

Quality Assessment

D
Quality Grade
Below average quality โ€” weak profitability or high leverage
2 quality flags detected โ€” see details below. These penalties are already factored into the final score.
Quality Flags
High accrual ratio (-612.0%) โ€” earnings quality concern
Pipeline concentration: $1.2B biotech/pharma โ€” likely single-product revenue with binary risk

Position Sizing

Suggested Allocation
3%
Confidence
high

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
100
Advancing
Sentiment (2.5%)
88
Positive
Analyst (6.4%)
69
Favorable
Tradability (post-hoc)
83
Grade A
Base
42.4
SHAP
+1.8
Factors
+0.8
Conviction
+1.4
Divergence
-2.9
Final
43.5
Positive adjustment
Negative adjustment
Base blend
Final score

Factor Breakdown

52AVG
Value15
Quality35
Growth70
Stability70
Investment68

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)47.0
Technical (Momentum, Weinstein, Volatility)83.0
External (Sentiment, Analyst, Macro)89.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage89%

Growth Estimates

Short-term
+1.2% to +5.9%
Medium-term
+2.8% to +10.0%
Long-term
+4.3% to +14.0%

ML Model Core Features100 trained inputs โ†’ ML Score: 20

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score69.4/100
Target Upside+64.3%
Coverage9 analysts
Market Sentiment
Sentiment Score87.8/100
News Volume1 articles
Technical Stage
Weinstein Stage2 โ€” Advancing
12M Momentum+2.3%
6M Momentum+2.7%
Volatility+0.3%
Momentum & Technical
Momentum Acceleration-47.5%
Momentum ConsistencyStrong (0.83)
Relative Strength vs Sector+201.4%
Trend Strength (ADX Proxy)Strong (5.0)
Momentum Quality+1.922
Momentum BreadthBroad โœ“
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
3%
Low risk
Sector RevGr Rank
P41
Revenue growth vs Healthcare peers
Sector PE Rank
P5
Valuation vs Healthcare peers
Sector FCF Rank
P94
Free cash flow vs Healthcare peers
Growth Deviation
-0.0ฯƒ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 54 relative to sector peers54/100
Machine learning ensemble ranks this stock at the 20th percentileP20
Blended score: 80% fundamental (54) + 20% ML (20) = 47.547.5
Risk assessment: low. Low vol 0.3%; Drawdown 15% โ†’ 0.0pt; Positive momentum 226% โ†’ -5.0ptLow
Earnings quality grade D: weak earnings quality, multiple concerns. Score adjusted by 0 pointsGrade D
SHAP feature alignment: +1.8pt (features align with model priorities)SHAP
Conviction adj: +1.4pt (conviction=N/A)Conviction
Divergence penalty: -2.9pt (ML 34pt lower)Divergence
Risk Factors
Quality concern: High accrual ratio (-612.0%) โ€” earnings quality concern; Pipeline concentration: $1.2B biotech/pharma โ€” likely single-product revenue with binary riskFlag

Sector Peer Comparison(Healthcare โ€” Rank #120 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
GLUE43.574.70.0%11.5%$1.2B
INCY89.915.821.2%25.0%$19.6B
GMAB86.113.122.8%36.4%$17.9B
CPRX83.713.723.5%37.6%$3.0B
ASND78.316.698.0%-31.7%$13.8B
EXEL78.315.17.0%33.7%$11.9B
VRTX78.232.18.9%32.9%$121.8B
NBIX75.126.521.4%16.7%$13.1B
RPRX75.025.15.1%32.4%$19.3B
HOLX74.831.11.7%13.8%$16.8B
AMGN74.226.010.0%21.0%$204.8B
ARGX73.735.178.6%38.0%$47.4B
REGN73.019.41.0%31.4%$80.2B
ALKS72.916.5-6.4%23.9%$5.0B
ISRG72.761.720.5%28.4%$180.9B
KRYS71.541.4473.0%30.7%$7.9B
Sector Average36.641.9161.5%-3292.7%โ€”

Market Sentimentvia FMP

Company Overviewvia FMP

Monte Rosa Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel small molecule precision medicines that employ the body's natural mechanisms to selectively degrade therapeutically relevant proteins. It develops an oral molecular glue degrader for GSPT1, a translational termination factor and degron-containing protein for the treatment of Myc-driven cancers. The company also develops CDK2 to treat ovarian, uterine, and breast cancers; NEK7 for the treatment of inflammatory diseases, such as Crohn's disease, neurodegenerative disease, diabetes, and liver disease; VAV1, a target protein for autoimmune diseases; and BCL11A, a therapeutically-relevant protein in hemoglobinopathies. Monte Rosa Therapeutics, Inc. was incorporated in 2019 and is headquartered in Boston, Massachusetts.

CEO
Markus Warmuth
Employees
142
Beta
1.62
Industry
Biotechnology
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
46.8
Neutral
Trend
Bearish
10-day vs 50-day MA
From 52W High
-28.2%
High: $25.77
From 52W Low
+428.6%
Low: $3.5
Moving Averages
10-Day
$18.70
Below
20-Day
$19.30
Below
50-Day
$19.70
Below
200-Day
$10.70
Above
60-Day Support
$13.69
60-Day Resistance
$25.77
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 2 โ€” AdvancingScore: 90/100

Stock is in an uptrend above the 200-day moving average. This is the stage where institutional accumulation typically occurs. The 50-day SMA provides support.

Favorable technical position; 50-day SMA acts as support
Price vs 200 SMA
+72.9%
200 SMA Slope (60d)
+63.74%
Rising
Volume Ratio
0.51x
10d avg vs 50d avg
Days in Stage
100
Confidence: 90%

Financial Statementslast 4 quarters via FMP

MetricQ3 2025Q2 2025Q1 2025Q4 2024
Revenue$13M$23M$85M$61M
Gross Profit$11M$23M$85M$61M
Operating Income$-33M$-16M$44M$13M
Net Income$-27M$-12M$47M$13M
EPS (Diluted)$-0.33$-0.15$0.57$0.22
Gross Margin83.6%100.0%100.0%100.0%
Operating Margin-258.3%-67.1%51.9%21.4%
Net Margin-212.1%-53.0%55.2%22.2%

Why This Stock

HealthcareProfit margin 11.5%

Tradability FilterGrade A โ€” 83/100Score impact: -13.4pt

Volume
100
1.6M avg/day
Dollar Vol
87
$31M/day
Float
72
42M shares
Mkt Cap
45
$1.2B
Range
100
636% spread
Composite Liquidity Score83/100
FDCBA

Multi-Year Range Analysis

Sideways: 0/100
YearLowHighRangeStatus
2021$15.67$45.5697.6%Wide
2022$6.05$21.56112.4%Wide
2023$2.44$8.83113.4%Wide
2024$3.21$12.40117.7%Wide
2025$3.50$19.17138.2%Wide
3-Year Range
154.8%
Narrow Years
0 / 5
Sideways Penalty
None
Free Float
64.7%
Outstanding Shares
65M
Bid-Ask Spread
636.0%
Institutional Tradable
Yes

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.