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26

JANX

🏥 Healthcare

Janux Therapeutics, Inc.

Conservative #1196Aggressive #417High RiskLow 25F↑ 22pt
$13.62-0.58%
Day High$13.72
Day Low$13.55
Volume0.0M
Mkt Cap$819M
52W Low $1252W High $36
Market Cap
$787M
P/E Ratio
N/A
Rev Growth
31.0%
Sector avg: 161.5%
Earnings Growth
-18.4%
Profit Margin
-1019.0%
Sector avg: -3292.7%
Debt/Equity
0.02

Why This Score

JANX scores 26.5 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Strengths
  • Minimal leverage (D/E 0.02) provides financial flexibility and downside protection.
  • ML model assigns a high-conviction signal (93/100), indicating strong pattern recognition across 82 features.
Risk Factors
  • Liquidity concern: Limited trading volume or float results in a 2-point penalty for execution risk.
  • Signal divergence: Fundamental and ML signals disagree by a significant margin, reducing confidence.
  • Above-average volatility (21.9%) may not suit conservative risk tolerance.

Net penalties of -18.8 points significantly impact the ranking. Without these adjustments, JANX would rank considerably higher.

Score Breakdown

Overall Score26.5
Fundamental Score28.5
ML Score93.0

Score by Horizon

3 Month
26.4
6 Month
29.5
Primary
1 Year
31.0

Quality Assessment

F
Earnings Grade
Weak fundamentals or significant quality concerns
Quality Flags
Pipeline concentration: $0.8B biotech/pharma — likely single-product revenue with binary risk
Speculative Classification
Anomalous margin data — extreme values suggest one-time events or accounting irregularities.
Conservative score reduced by 4 points.

Position Sizing

Suggested Allocation
3.6%
Confidence
high

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
0
Declining
Sentiment (2.5%)
58
Neutral
Analyst (6.4%)
71
Favorable
Tradability (post-hoc)
75
Grade B
Base
35.4
SHAP
+1.2
Factors
-0.3
Conviction
-2.4
Divergence
-7.4
Final
26.5
Positive adjustment
Negative adjustment
Base blend
Final score

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)54.0
Technical (Momentum, Weinstein, Volatility)23.0
External (Sentiment, Analyst, Macro)82.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage89%

Growth Estimates

Short-term
-7.9% to -2.9%
Medium-term
-10.8% to -3.5%
Long-term
-13.8% to -4.1%

ML Model Core Features100 trained inputs → ML Score: 93

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score70.8/100
Target Upside+243.2%
Coverage12 analysts
Market Sentiment
Sentiment Score58.3/100
News Volume1 articles
Technical Stage
Weinstein Stage4 — Declining
12M Momentum-0.6%
6M Momentum-0.4%
Volatility+0.2%
Momentum & Technical
Momentum Acceleration-17.9%
Momentum ConsistencyStrong (0.70)
Relative Strength vs Sector-84.5%
Trend Strength (ADX Proxy)Moderate (2.7)
Momentum Quality-0.231
Momentum BreadthNarrow
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
2%
Low risk
Sector RevGr Rank
P77
Revenue growth vs Healthcare peers
Sector PE Rank
P40
Valuation vs Healthcare peers
Sector FCF Rank
P24
Free cash flow vs Healthcare peers
Growth Deviation
+0.0σ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 62 relative to sector peers62/100
Machine learning model ranks this stock at the 39th percentileP39
ML model weight reduced to 9% due to macro conditions: market in extended rally phase; yield curve inverted (recession indicator); late-cycle economic indicators detected9% ML weight
SHAP feature alignment: +1.2pt (features align with model priorities)—
Blend: 91% fund (61.6) + 9% ML (38.2) + SHAP(+1.2) = 60.7—
Factor quality: -0.3pt (multi-factor composite)—
Market cap adjustment: -15.0 points ($0.8B market cap)-15.0 pts
Conviction penalty: -2.4pt (conviction=25)—
Divergence penalty: -1.8pt (fund 22pt higher)—
Risk Factors
Risk assessment: high. Annualized volatility 22.0%. Max drawdown 61% (-12.0 pts). Price momentum -60% (-10.0 pts)High
Earnings quality grade F: assessed. Score adjusted by -30 pointsGrade F
Quality concern: Non-operating gain: net margin (-1019.0%) exceeds operating margin (-1442.9%) by 424pp — likely one-time item; High accrual ratio (30.9%) — earnings quality concern; Pipeline concentration: $0.8B biotech/pharma — likely single-product revenue with binary riskFlag

Sector Peer Comparison(Healthcare — Rank #249 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
JANX26.5N/A31.0%-1019.0%$787M
INCY89.615.821.2%25.0%$20.1B
GMAB85.513.122.8%36.4%$18.5B
CPRX82.213.723.5%37.6%$3.0B
VRTX78.032.18.9%32.9%$126.0B
ASND75.716.698.0%-31.7%$13.3B
NBIX74.726.521.4%16.7%$12.5B
ALKS74.616.5-6.4%23.9%$5.5B
AMGN73.826.010.0%21.0%$199.0B
ARGX73.635.178.6%38.0%$50.9B
HOLX73.331.11.7%13.8%$16.8B
REGN72.719.41.0%31.4%$84.9B
ISRG72.361.720.5%28.4%$172.5B
EXEL71.915.17.0%33.7%$11.7B
KRYS71.041.4473.0%30.7%$8.0B
HALO70.216.822.4%43.7%$9.3B
Sector Average37.1252.3161.5%-3292.7%—

Market Sentimentvia FMP

Analyst Consensus
Buy12 analysts
Buy: 10Hold: 2
Price Target
$45consensus
Low $29Median $42High $72
+231.6% to consensus target

Company Overviewvia FMP

Janux Therapeutics, Inc., a biopharmaceutical company, develops therapeutics based on proprietary Tumor Activated T Cell Engager (TRACTr) platform technology to treat patients suffering from cancer. The company's lead TRACTr product candidates that are in preclinical or discovery stage target prostate-specific membrane antigen, epidermal growth factor receptor, and trophoblast cell surface antigen 2. Janux Therapeutics, Inc. is also developing a Tumor Activated Immunomodulator (TRACIr) costimulatory bispecific product candidate against programmed death-ligand 1 and CD28 designed to improve the anti-tumor activity of T cells. In addition, its EGFR-TRACTr is designed to target EGFR in many cancer types with multiple approved monoclonal antibodies. The company was incorporated in 2017 and is headquartered in La Jolla, California.

CEO
David Alan Campbell
Employees
91
Beta
2.87
Industry
Biotechnology
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
78.9
Overbought
Trend
Bearish
10-day vs 50-day MA
From 52W High
-61.3%
High: $35.34
From 52W Low
+12.7%
Low: $12.12
Moving Averages
10-Day
$13.40
Above
20-Day
$13.30
Above
50-Day
$13.80
Below
200-Day
$22.10
Below
60-Day Support
$12.12
60-Day Resistance
$34.04
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 4 — DecliningScore: 10/100

Stock is in a downtrend below the 200-day moving average. Price is below both the 50-day and 200-day SMAs, indicating sustained selling pressure.

Unfavorable technical position; wait for Stage 1 basing
Price vs 200 SMA
-38.2%
200 SMA Slope (60d)
-17.91%
Falling
Volume Ratio
0.51x
10d avg vs 50d avg
Days in Stage
59
Confidence: 90%

Financial Statementslast 4 quarters via FMP

MetricQ3 2025Q2 2025Q1 2025Q4 2024
Revenue$10M$0$0$0
Gross Profit$9M$0$0$0
Operating Income$-35M$-45M$-35M$-29M
Net Income$-24M$-34M$-24M$-20M
EPS (Diluted)$-0.39$-0.55$-0.38$-0.36
Gross Margin95.0%N/AN/AN/A
Operating Margin-352.5%N/AN/AN/A
Net Margin-243.1%N/AN/AN/A

Why This Stock

HealthcareRevenue growth 31.0%

Tradability FilterGrade B — 75/100Score impact: -38.4pt

Volume
100
2.1M avg/day
Dollar Vol
86
$29M/day
Float
40
0K shares
Mkt Cap
36
$787M
Range
100
199% spread
Composite Liquidity Score75/100
FDCBA

Multi-Year Range Analysis

Sideways: 0/100
YearLowHighRangeStatus
2021$14.39$37.9990.1%Wide
2022$9.39$20.8575.8%Wide
2023$5.65$23.64122.8%Wide
2024$7.79$71.71160.8%Wide
2025$13.62$61.59127.6%Wide
3-Year Range
170.8%
Narrow Years
0 / 5
Sideways Penalty
None

Growth Projection Adjustment

0.7x dampening
weinstein basing

Growth estimates have been dampened based on technical and fundamental signals. This is a post-hoc adjustment to prevent overly optimistic projections for stocks showing declining momentum or deteriorating fundamentals.

Free Float
0.0%
Outstanding Shares
0M
Bid-Ask Spread
199.0%
Institutional Tradable
Yes

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.