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19

DSGN

๐Ÿฅ Healthcare

Design Therapeutics, Inc.

Conservative #1287Aggressive #1064Moderate RiskFโ†‘ 38pt
$10.68-2.64%
Day High$10.81
Day Low$10.42
Volume0.1M
Mkt Cap$608M
52W Low $352W High $11
Market Cap
$616M
P/E Ratio
N/A
Rev Growth
0.0%
Sector avg: 161.5%
Earnings Growth
25.8%
Profit Margin
0.0%
Sector avg: -3292.7%
Debt/Equity
0.01

Why This Score

DSGN scores 19.4 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Strengths
  • Minimal leverage (D/E 0.01) provides financial flexibility and downside protection.
Risk Factors
  • Liquidity concern: Limited trading volume or float results in a 5-point penalty for execution risk.
  • Signal divergence: Fundamental and ML signals disagree by a significant margin, reducing confidence.
  • Above-average volatility (22.4%) may not suit conservative risk tolerance.

Net penalties of -15.3 points significantly impact the ranking. Without these adjustments, DSGN would rank considerably higher.

Score Breakdown

Overall Score19.4
Fundamental Score37.1
ML Score8.0

Score by Horizon

3 Month
15.8
6 Month
17.6
Primary
1 Year
18.6

Quality Assessment

F
Quality Grade
Low quality โ€” significant fundamental weaknesses
1 quality flag detected โ€” see details below. These penalties are already factored into the final score.
Quality Flags
Pipeline concentration: $0.6B biotech/pharma โ€” likely single-product revenue with binary risk
Speculative Classification
Speculative micro-cap โ€” no earnings, sub-$2B market cap, momentum-driven. Position sizing should reflect elevated risk.
Conservative score reduced by 3 points.

Position Sizing

Suggested Allocation
3.6%
Confidence
high

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
100
Advancing
Sentiment (2.5%)
82
Positive
Analyst (6.4%)
63
Favorable
Tradability (post-hoc)
55
Grade Clow dollar volume
Base
23.2
SHAP
+0.9
Factors
-0.2
Conviction
-2.4
Divergence
-2.1
Final
19.4
Positive adjustment
Negative adjustment
Base blend
Final score

Factor Breakdown

38AVG
Value50
Quality7
Growth59
Stability65
Investment10

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)56.0
Technical (Momentum, Weinstein, Volatility)79.0
External (Sentiment, Analyst, Macro)86.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage89%

Growth Estimates

Short-term
-7.9% to -2.5%
Medium-term
-10.7% to -2.8%
Long-term
-13.4% to -3.2%

ML Model Core Features100 trained inputs โ†’ ML Score: 8

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score62.5/100
Target Upside+52.1%
Coverage6 analysts
Market Sentiment
Sentiment Score82.0/100
News Volume1 articles
Technical Stage
Weinstein Stage2 โ€” Advancing
12M Momentum+1.1%
6M Momentum+0.8%
Volatility+0.2%
Momentum & Technical
Momentum Acceleration+25.1%
Momentum ConsistencyStrong (0.77)
Relative Strength vs Sector+82.8%
Trend Strength (ADX Proxy)Strong (4.8)
Momentum Quality+0.743
Momentum BreadthBroad โœ“
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
3%
Low risk
Sector RevGr Rank
P41
Revenue growth vs Healthcare peers
Sector PE Rank
P22
Valuation vs Healthcare peers
Sector FCF Rank
P24
Free cash flow vs Healthcare peers
Growth Deviation
-0.0ฯƒ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 37 relative to sector peers37/100
Machine learning ensemble ranks this stock at the 8th percentileP8
Blended score: 80% fundamental (37) + 20% ML (8) = 31.331.3
Risk assessment: low. Low vol 0.2%; Drawdown 31% โ†’ 0.0ptLow
Earnings quality grade F: quality flags triggered โ€” see details below. Score adjusted by 0 pointsGrade F
SHAP feature alignment: +0.9pt (features align with model priorities)SHAP
Conviction adj: -2.4pt (conviction=N/A)Conviction
Divergence penalty: -2.1pt (ML 29pt lower)Divergence
Risk Factors
Quality concern: Pipeline concentration: $0.6B biotech/pharma โ€” likely single-product revenue with binary riskFlag
Speculative: SPEC_MICRO (3.0pt penalty)Speculative
Liquidity penalty: -5.0pt (grade C)Liquidity

Sector Peer Comparison(Healthcare โ€” Rank #282 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
DSGN19.4N/A0.0%0.0%$616M
INCY89.915.821.2%25.0%$19.6B
GMAB86.113.122.8%36.4%$17.9B
CPRX83.713.723.5%37.6%$3.0B
ASND78.316.698.0%-31.7%$13.8B
EXEL78.315.17.0%33.7%$11.9B
VRTX78.232.18.9%32.9%$121.8B
NBIX75.126.521.4%16.7%$13.1B
RPRX75.025.15.1%32.4%$19.3B
HOLX74.831.11.7%13.8%$16.8B
AMGN74.226.010.0%21.0%$204.8B
ARGX73.735.178.6%38.0%$47.4B
REGN73.019.41.0%31.4%$80.2B
ALKS72.916.5-6.4%23.9%$5.0B
ISRG72.761.720.5%28.4%$180.9B
KRYS71.541.4473.0%30.7%$7.9B
Sector Average36.641.9161.5%-3292.7%โ€”

Company Overviewvia FMP

Design Therapeutics, Inc. a preclinical-stage biopharmaceutical company, engages in the development of therapies for the treatment of genetic diseases caused by nucleotide repeat expansions. The company's portfolio of products comprises Friedreich Ataxia, a monogenic, autosomal recessive, progressive multi-system disease that affects organ systems dependent on mitochondrial function, eventually leading to neurological, cardiac, and metabolic dysfunction; and Myotonic Dystrophy Type-1 (DM1), a dominantly-inherited, monogenic progressive neuromuscular disease affecting skeletal muscle, heart, brain, and other organs. It is also developing GeneTAC product candidate portfolio for the treatment of other nucleotide repeat expansion-driven monogenic diseases, such as Fragile X syndrome, spinocerebellar ataxias, amyotrophic lateral sclerosis, frontotemporal dementia, Huntington disease, and spinobulbar muscular atrophy. Design Therapeutics, Inc. was incorporated in 2017 and is headquartered in Carlsbad, California.

CEO
Pratik Shah
Employees
56
Beta
1.64
Industry
Biotechnology
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
63.3
Neutral
Trend
Bullish
10-day vs 50-day MA
From 52W High
-4.1%
High: $11.14
From 52W Low
+310.8%
Low: $2.6
Moving Averages
10-Day
$10.30
Above
20-Day
$10.30
Above
50-Day
$9.90
Above
200-Day
$6.60
Above
60-Day Support
$8.23
60-Day Resistance
$11.14
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 2 โ€” AdvancingScore: 90/100

Stock is in an uptrend above the 200-day moving average. This is the stage where institutional accumulation typically occurs. The 50-day SMA provides support.

Favorable technical position; 50-day SMA acts as support
Price vs 200 SMA
+61.8%
200 SMA Slope (60d)
+33.68%
Rising
Volume Ratio
0.56x
10d avg vs 50d avg
Days in Stage
100
Confidence: 90%

Financial Statementslast 4 quarters via FMP

MetricQ3 2025Q2 2025Q1 2025Q4 2024
Revenue$0$0$0$0
Gross Profit$-15M$-152,000$0$0
Operating Income$-19M$-22M$-20M$-17M
Net Income$-17M$-19M$-18M$-14M
EPS (Diluted)$-0.30$-0.34$-0.31$-0.24
Gross MarginN/AN/AN/AN/A
Operating MarginN/AN/AN/AN/A
Net MarginN/AN/AN/AN/A

Why This Stock

Healthcare

Tradability FilterGrade C โ€” 55/100Score impact: -28.2pt

Volume
65
353K avg/day
Dollar Vol
33
$4M/day
Float
61
31M shares
Mkt Cap
32
$616M
Range
100
322% spread
Composite Liquidity Score55/100
FDCBA
low dollar volume

Multi-Year Range Analysis

Sideways: 0/100
YearLowHighRangeStatus
2021$12.52$50.50120.5%Wide
2022$6.94$26.30116.5%Wide
2023$1.94$10.72138.7%Wide
2024$2.25$7.77110.2%Wide
2025$2.60$10.31119.4%Wide
3-Year Range
138.7%
Narrow Years
0 / 5
Sideways Penalty
None
Free Float
55.2%
Outstanding Shares
57M
Bid-Ask Spread
322.0%
Institutional Tradable
Limited

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.