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54

BLFS

🏥 Healthcare

BioLife Solutions, Inc.

Conservative #461Aggressive #454Low RiskHigh 80
$22.28-0.85%
Day High$22.73
Day Low$22.28
Volume0.1M
Mkt Cap$1.1B
52W Low $1952W High $30
Market Cap
$1.1B
P/E Ratio
N/A
Rev Growth
-42.6%
Sector avg: 161.5%
Earnings Growth
69.6%
Profit Margin
-4.3%
Sector avg: -3292.7%
Debt/Equity
0.06

Why This Score

BLFS scores 53.7 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Strengths
  • Minimal leverage (D/E 0.06) provides financial flexibility and downside protection.
  • High conviction (80/100) — fundamental and ML signals agree on this stock.
Risk Factors
  • Liquidity concern: Limited trading volume or float results in a 2-point penalty for execution risk.
  • Signal divergence: Fundamental and ML signals disagree by a significant margin, reducing confidence.

Moderate penalties (-5.2 points) reflect identified risk factors. The overall score balances these against the stock's fundamental strengths.

Score Breakdown

Overall Score53.7
Fundamental Score47.6
ML Score84.0

Score by Horizon

3 Month
66.1
6 Month
73.9
Primary
1 Year
77.8

Quality Assessment

F
Earnings Grade
Weak fundamentals or significant quality concerns
Quality Flags
High accrual ratio (625.4%) — earnings quality concern

Position Sizing

Suggested Allocation
5%
Confidence
high

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
50
Basing
Sentiment (2.5%)
46
Neutral
Analyst (6.4%)
75
Favorable
Tradability (post-hoc)
63
Grade B
Base
52.9
SHAP
+1.5
Factors
+1.4
Conviction
+1.0
Divergence
-3.2
Final
53.7
Positive adjustment
Negative adjustment
Base blend
Final score

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)50.0
Technical (Momentum, Weinstein, Volatility)54.0
External (Sentiment, Analyst, Macro)68.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage89%

Growth Estimates

Short-term
-1.7% to +4.7%
Medium-term
-2.3% to +7.3%
Long-term
-2.9% to +10.0%

ML Model Core Features100 trained inputs → ML Score: 84

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score75.0/100
Target Upside+0.0%
Coverage17 analysts
Market Sentiment
Sentiment Score46.0/100
News Volume0 articles
Technical Stage
Weinstein Stage1 — Basing
12M Momentum-0.1%
6M Momentum-0.1%
Volatility+0.1%
Momentum & Technical
Momentum Acceleration+3.9%
Momentum ConsistencyModerate (0.66)
Relative Strength vs Sector-31.8%
Trend Strength (ADX Proxy)Weak (0.9)
Momentum Quality-0.058
Momentum BreadthNarrow
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
13%
Low risk
Sector RevGr Rank
P7
Revenue growth vs Healthcare peers
Sector PE Rank
P22
Valuation vs Healthcare peers
Sector FCF Rank
P63
Free cash flow vs Healthcare peers
Growth Deviation
-0.0σ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 77 relative to sector peers77/100
Machine learning model ranks this stock at the 77th percentileP77
ML model weight reduced to 9% due to macro conditions: market in extended rally phase; yield curve inverted (recession indicator); late-cycle economic indicators detected9% ML weight
SHAP feature alignment: +1.8pt (features align with model priorities)
Blend: 91% fund (77.3) + 9% ML (75.1) + SHAP(+1.8) = 78.9
Factor quality: +1.7pt (multi-factor composite)
Risk assessment: low. Annualized volatility 7.9%. Max drawdown 22% (-5.5 pts). Price momentum -7% (-0.5 pts)Low
Market cap adjustment: -8.0 points ($1.1B market cap)-8.0 pts
Conviction bonus: +1.2pt (conviction=80)
Risk Factors
Earnings quality grade F: assessed. Score adjusted by -27 pointsGrade F
Quality concern: Elevated non-operating income: 18pp gap between net and operating margin; Earnings/revenue growth ratio of Infinityx — earnings quality suspect; High accrual ratio (625.4%) — earnings quality concernFlag

Sector Peer Comparison(Healthcare — Rank #59 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
BLFS53.7N/A-42.6%-4.3%$1.1B
INCY89.615.821.2%25.0%$19.6B
GMAB85.613.122.8%36.4%$17.9B
CPRX82.113.723.5%37.6%$3.0B
VRTX78.032.18.9%32.9%$121.8B
ASND75.816.698.0%-31.7%$13.8B
NBIX74.826.521.4%16.7%$13.1B
AMGN73.926.010.0%21.0%$204.8B
ARGX73.535.178.6%38.0%$47.4B
HOLX73.331.11.7%13.8%$16.8B
REGN72.419.41.0%31.4%$80.2B
ISRG72.261.720.5%28.4%$180.9B
EXEL71.615.17.0%33.7%$11.9B
ALKS71.516.5-6.4%23.9%$5.0B
KRYS71.041.4473.0%30.7%$7.9B
HALO70.316.822.4%43.7%$8.2B
Sector Average37.041.9161.5%-3292.7%

Company Overviewvia FMP

BioLife Solutions, Inc. develops, manufactures, and supplies bioproduction tools and services for the cell and gene therapy industry in the United States, Canada, Europe, the Middle East, Africa, and internationally. The company's products are used in the basic and applied research, and commercial manufacturing of biologic-based therapies. It offers proprietary biopreservation media products, including HypoThermosol FRS and CryoStor that are formulated to mitigate preservation-induced, delayed-onset cell damage and death; and the ThawSTAR line that includes automated vial and cryobag thawing products that control the heat and timing of the thawing process of biologic materials. The company also provides evo shipping containers that are cloud-connected passive storage and transport containers for temperature-sensitive biologics and pharmaceuticals; liquid nitrogen laboratory freezers, cryogenic equipment, and accessories; and biological and pharmaceutical storage services. It markets and sells its products directly, as well as through third party distributors. BioLife Solutions, Inc. was incorporated in 1987 and is headquartered in Bothell, Washington.

CEO
Roderick de Greef
Employees
159
Beta
1.92
Industry
Medical - Instruments & Supplies
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
53.7
Neutral
Trend
Bearish
10-day vs 50-day MA
From 52W High
-24.6%
High: $29.62
From 52W Low
+16.9%
Low: $19.1
Moving Averages
10-Day
$22.60
Below
20-Day
$22.50
Below
50-Day
$23.90
Below
200-Day
$24.20
Below
60-Day Support
$21.35
60-Day Resistance
$26.68
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 1 — BasingScore: 43/100

Stock is building a base after a decline. The 200-day moving average is flattening. Watch for a breakout above the 200-day SMA on increased volume.

Monitor for breakout above 200-day SMA on volume
Price vs 200 SMA
-7.7%
200 SMA Slope (60d)
-0.37%
Flattening
Volume Ratio
0.79x
10d avg vs 50d avg
Days in Stage
21
Confidence: 70%

Financial Statementslast 4 quarters via FMP

MetricQ3 2025Q2 2025Q1 2025Q4 2024
Revenue$28M$25M$24M$-3M
Gross Profit$17M$16M$16M$8M
Operating Income$-89,000$-17M$-1M$1M
Net Income$621,000$-16M$-448,000$12M
EPS (Diluted)$0.01$-0.33$-0.01$0.26
Gross Margin61.4%64.6%65.9%N/A
Operating Margin-0.3%-65.5%-5.1%N/A
Net Margin2.2%-62.3%-1.9%N/A

Why This Stock

Healthcare

Tradability FilterGrade B — 63/100Score impact: -18.2pt

Volume
65
348K avg/day
Dollar Vol
56
$8M/day
Float
71
41M shares
Mkt Cap
42
$1.1B
Range
88
55% spread
Composite Liquidity Score63/100
FDCBA

Multi-Year Range Analysis

Sideways: 0/100
YearLowHighRangeStatus
2021$28.15$60.6773.2%Wide
2022$10.40$38.01114.1%Wide
2023$8.92$26.89100.4%Wide
2024$14.50$28.8866.3%Wide
2025$19.10$29.6243.2%Wide
3-Year Range
107.4%
Narrow Years
0 / 5
Sideways Penalty
None

Growth Projection Adjustment

0.21x dampening
weinstein basingsevere revenue decline

Growth estimates have been dampened based on technical and fundamental signals. This is a post-hoc adjustment to prevent overly optimistic projections for stocks showing declining momentum or deteriorating fundamentals.

Free Float
84.8%
Outstanding Shares
48M
Bid-Ask Spread
55.0%
Institutional Tradable
Yes

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.