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21

ENTA

๐Ÿฅ Healthcare

Enanta Pharmaceuticals, Inc.

Conservative #1262Aggressive #1158Moderate Risk
$14.30-0.76%
Day High$14.32
Day Low$13.88
Volume0.1M
Mkt Cap$332M
52W Low $452W High $17
Market Cap
$336M
P/E Ratio
N/A
Rev Growth
-3.4%
Sector avg: 161.5%
Earnings Growth
29.4%
Profit Margin
-106.8%
Sector avg: -3292.7%
Debt/Equity
0.45

Why This Score

ENTA scores 21.2 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Strengths
  • High conviction (78/100) โ€” fundamental and ML signals agree on this stock.
Risk Factors
  • Liquidity concern: Limited trading volume or float results in a 5-point penalty for execution risk.
  • Signal divergence: Fundamental and ML signals disagree by a significant margin, reducing confidence.
  • Above-average volatility (19.4%) may not suit conservative risk tolerance.

Net penalties of -13.9 points significantly impact the ranking. Without these adjustments, ENTA would rank considerably higher.

Score Breakdown

Overall Score21.2
Fundamental Score39.5
ML Score5.0

Score by Horizon

3 Month
36.8
6 Month
41.1
Primary
1 Year
43.2

Quality Assessment

F
Quality Grade
Low quality โ€” significant fundamental weaknesses
1 quality flag detected โ€” see details below. These penalties are already factored into the final score.
Quality Flags
Pipeline concentration: $0.3B biotech/pharma โ€” likely single-product revenue with binary risk
Speculative Classification
Speculative growth โ€” negative margins and ROE with momentum-driven price action. High risk of mean reversion.
Speculative micro-cap โ€” no earnings, sub-$2B market cap, momentum-driven. Position sizing should reflect elevated risk.
Conservative score reduced by 6 points.

Position Sizing

Suggested Allocation
4.1%
Confidence
high

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
100
Advancing
Sentiment (2.5%)
82
Positive
Analyst (6.4%)
66
Favorable
Tradability (post-hoc)
49
Grade Clow dollar volume, small cap
Base
21.5
SHAP
+1.8
Factors
+0.8
Divergence
-2.9
Final
21.2
Positive adjustment
Negative adjustment
Base blend
Final score

Factor Breakdown

39AVG
Value50
Quality0
Growth59
Stability73
Investment14

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)54.0
Technical (Momentum, Weinstein, Volatility)85.0
External (Sentiment, Analyst, Macro)87.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage89%

Growth Estimates

Short-term
-3.8% to +0.5%
Medium-term
-5.4% to +1.0%
Long-term
-7.0% to +1.4%

ML Model Core Features100 trained inputs โ†’ ML Score: 5

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score65.8/100
Target Upside+48.4%
Coverage19 analysts
Market Sentiment
Sentiment Score82.0/100
News Volume1 articles
Technical Stage
Weinstein Stage2 โ€” Advancing
12M Momentum+0.8%
6M Momentum+0.6%
Volatility+0.2%
Momentum & Technical
Momentum Acceleration+13.1%
Momentum ConsistencyStrong (0.83)
Relative Strength vs Sector+53.6%
Trend Strength (ADX Proxy)Strong (4.0)
Momentum Quality+0.638
Momentum BreadthBroad โœ“
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
6%
Low risk
Sector RevGr Rank
P15
Revenue growth vs Healthcare peers
Sector PE Rank
P22
Valuation vs Healthcare peers
Sector FCF Rank
P33
Free cash flow vs Healthcare peers
Growth Deviation
-0.0ฯƒ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 40 relative to sector peers40/100
Machine learning ensemble ranks this stock at the 5th percentileP5
Blended score: 80% fundamental (40) + 20% ML (5) = 32.632.6
Risk assessment: low. Low vol 0.2%; Drawdown 18% โ†’ 0.0ptLow
Earnings quality grade F: quality flags triggered โ€” see details below. Score adjusted by 0 pointsGrade F
SHAP feature alignment: +1.8pt (features align with model priorities)SHAP
Divergence penalty: -2.9pt (ML 35pt lower)Divergence
Risk Factors
Quality concern: Pipeline concentration: $0.3B biotech/pharma โ€” likely single-product revenue with binary riskFlag
Speculative: SPEC_GROWTH, SPEC_MICRO (6.0pt penalty)Speculative
Liquidity penalty: -5.0pt (grade C)Liquidity

Sector Peer Comparison(Healthcare โ€” Rank #272 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
ENTA21.2N/A-3.4%-106.8%$336M
INCY89.915.821.2%25.0%$20.2B
GMAB86.113.122.8%36.4%$18.1B
CPRX83.713.723.5%37.6%$2.9B
ASND78.316.698.0%-31.7%$14.0B
EXEL78.315.17.0%33.7%$11.9B
VRTX78.232.18.9%32.9%$125.2B
NBIX75.126.521.4%16.7%$13.3B
RPRX75.025.15.1%32.4%$19.8B
HOLX74.831.11.7%13.8%$16.8B
AMGN74.226.010.0%21.0%$210.2B
ARGX73.735.178.6%38.0%$48.0B
REGN73.019.41.0%31.4%$81.3B
ALKS72.916.5-6.4%23.9%$5.0B
ISRG72.761.720.5%28.4%$177.8B
KRYS71.541.4473.0%30.7%$8.0B
Sector Average36.641.9161.5%-3292.7%โ€”

Company Overviewvia FMP

Enanta Pharmaceuticals, Inc., a biotechnology company, discovers and develops small molecule drugs for the treatment of viral infections and liver diseases. Its research and development disease targets include respiratory syncytial virus, SARS-CoV-2, human metapneumovirus, and hepatitis B virus. The company has a collaborative development and license agreement with Abbott Laboratories to identify, develop, and commercialize HCV NS3 and NS3/4A protease inhibitor compounds, including paritaprevir and glecaprevir for the treatment of chronic hepatitis C virus. Enanta Pharmaceuticals, Inc. was founded in 1995 and is headquartered in Watertown, Massachusetts.

CEO
Jay R. Luly
Employees
131
Beta
0.99
Industry
Biotechnology
FMP-Identified Peers

Technical Picturecomputed from daily prices

RSI (14)
61.2
Neutral
Trend
Bullish
10-day vs 50-day MA
From 52W High
-16.6%
High: $17.15
From 52W Low
+249.6%
Low: $4.09
Moving Averages
10-Day
$14.10
Above
20-Day
$13.80
Above
50-Day
$14.00
Above
200-Day
$10.40
Above
60-Day Support
$12.09
60-Day Resistance
$17.15
Weinstein Stage Analysisbased on 200-day SMA framework
Stage 2 โ€” AdvancingScore: 90/100

Stock is in an uptrend above the 200-day moving average. This is the stage where institutional accumulation typically occurs. The 50-day SMA provides support.

Favorable technical position; 50-day SMA acts as support
Price vs 200 SMA
+37.5%
200 SMA Slope (60d)
+29.66%
Rising
Volume Ratio
0.7x
10d avg vs 50d avg
Days in Stage
100
Confidence: 90%

Entry & Exit Zones

In Entry Zone
$9.88
Stop Entry Now Target
$17.77
Entry Zone
$13.86 โ€“ $14.42
SMA50 pullback zone ($13.86โ€“$14.42)
Exit Target
$17.25
52-week high / +22% target ($17.25)
Stop Level
$10.19
Below SMA200 ($10.19)
Risk / Reward:1 : 0.79Tight

Stage 2 uptrend โ€” institutional accumulation phase. SMA50 pullbacks are the highest-probability entry points. Stop below SMA200 preserves capital if trend breaks.

Technical zones only โ€” derived from moving averages and price structure. Not financial advice. Past technical patterns do not guarantee future performance.

Financial Statementslast 4 quarters via FMP

MetricQ1 2025Q4 2025Q3 2025Q2 2025
Revenue$19M$15M$18M$15M
Gross Profit$19M$15M$18M$15M
Operating Income$-11M$-18M$-19M$-25M
Net Income$-12M$-19M$-18M$-23M
EPS (Diluted)$-0.56$-0.87$-0.86$-1.06
Gross Margin100.0%100.0%100.0%100.0%
Operating Margin-60.5%-121.6%-103.2%-164.3%
Net Margin-64.1%-123.6%-99.7%-151.7%

Why This Stock

Healthcare

Tradability FilterGrade C โ€” 49/100Score impact: -29.2pt

Volume
60
299K avg/day
Dollar Vol
38
$4M/day
Float
51
21M shares
Mkt Cap
11
$336M
Range
100
319% spread
Composite Liquidity Score49/100
FDCBA
low dollar volumesmall cap

Multi-Year Range Analysis

Sideways: 0/100
YearLowHighRangeStatus
2021$40.37$102.0086.6%Wide
2022$37.59$79.5071.6%Wide
2023$8.08$62.06153.9%Wide
2024$5.30$17.80108.2%Wide
2025$4.09$17.15123%Wide
3-Year Range
175.3%
Narrow Years
0 / 5
Sideways Penalty
None

Growth Projection Adjustment

0.7x dampening
slight revenue decline

Growth estimates have been dampened based on technical and fundamental signals. This is a post-hoc adjustment to prevent overly optimistic projections for stocks showing declining momentum or deteriorating fundamentals.

Free Float
89.8%
Outstanding Shares
23M
Bid-Ask Spread
319.0%
Institutional Tradable
Limited

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.