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17

AKTS

๐Ÿฅ Healthcare

Aktis Oncology, Inc.

Conservative #1313Aggressive #1329Moderate RiskFโ†‘ 16pt
$20.13+2.55%
Day High$20.41
Day Low$19.03
Volume0.1M
Mkt Cap$1.1B
52W Low $1752W High $29
Market Cap
$993M
P/E Ratio
N/A
Rev Growth
0.0%
Sector avg: 161.5%
Earnings Growth
-53.6%
Profit Margin
-2957.6%
Sector avg: -3292.7%
Debt/Equity
N/A

Why This Score

AKTS scores 17.8 on the Conservative profile, blending a fundamental score (80% weight, emphasizing quality and stability (84% of fundamental weight)) with a machine-learning signal (20% weight) trained on 82 features across 30 years of data.

Strengths
  • Strong profitability: ROE of 65.6% exceeds the 15% quality threshold.
  • Minimal leverage (D/E -0.14) provides financial flexibility and downside protection.
Risk Factors
  • Liquidity concern: Limited trading volume or float results in a 25-point penalty for execution risk.
  • Above-average volatility (20.0%) may not suit conservative risk tolerance.

Net penalties of -34.7 points significantly impact the ranking. Without these adjustments, AKTS would rank considerably higher.

Score Breakdown

Overall Score17.8
Fundamental Score50.1
ML Score48.0

Score by Horizon

3 Month
29.7
6 Month
33.1
Primary
1 Year
34.9

Quality Assessment

D
Quality Grade
Below average quality โ€” weak profitability or high leverage
2 quality flags detected โ€” see details below. These penalties are already factored into the final score.
Quality Flags
Negative ROIC (-16.9%) with high ROE (65.6%) โ€” capital structure distortion (possibly negative equity or one-time gain)
Pipeline concentration: $1.0B biotech/pharma โ€” likely single-product revenue with binary risk
Speculative Classification
Anomalous margin data โ€” extreme values suggest one-time events or accounting irregularities.
Conservative score reduced by 4 points.

Position Sizing

Suggested Allocation
4%
Confidence
medium

Score Composition Waterfall

How each component affects the final score
Backtested Scoring Levers (IC-calibrated from 30y ElasticNet)
Weinstein (12.1%)
50
Basing
Sentiment (2.5%)
66
Positive
Analyst (6.4%)
63
Favorable
Tradability (post-hoc)
0
Grade Fvery low float
Base
20.6
SHAP
-1.2
Factors
-0.5
Conviction
-1.1
Final
17.8
Positive adjustment
Negative adjustment
Base blend
Final score

Factor Breakdown

40AVG
Value50
Quality33
Growth20
Stability60
Investment35

Signal SegmentsComputed from ML features

Fundamental (Valuation, Quality, Growth)58.0
Technical (Momentum, Weinstein, Volatility)52.0
External (Sentiment, Analyst, Macro)82.0
Scores below 50 indicate weakness in that segment relative to the universe.

Data Quality

Score
Features
Confidence
Feature Coverage72%

Growth Estimates

Short-term
-9.1% to -3.6%
Medium-term
-12.2% to -4.3%
Long-term
-15.4% to -5.0%

ML Model Core Features100 trained inputs โ†’ ML Score: 48

These features are direct inputs to the machine learning model. The model was trained on these signals alongside 100 features (including 12 momentum/technical indicators) to produce the ML percentile score.

Analyst Intelligence
Consensus Score62.5/100
Target Upside+63.0%
Coverage6 analysts
Market Sentiment
Sentiment Score66.3/100
News Volume1 articles
Technical Stage
Weinstein Stage1 โ€” Basing
Volatility+0.2%
Momentum & Technical
Momentum Acceleration+0.0%
Momentum ConsistencyDivergent (0.00)
Relative Strength vs Sector-24.4%
Trend Strength (ADX Proxy)Weak (0.0)
Momentum Quality+0.000
Momentum BreadthNarrow
Macro Regime
Bull RegimeYes
High Vol RegimeNo
S&P 500 Return+25.0%
Yield Curve-0.1bp

Sector-Relative AnalysisIn-model features

Value Trap Signal
8%
Low risk
Sector RevGr Rank
P41
Revenue growth vs Healthcare peers
Sector PE Rank
P22
Valuation vs Healthcare peers
Sector FCF Rank
P65
Free cash flow vs Healthcare peers
Growth Deviation
-0.0ฯƒ
Z-score vs sector median
Stagnation Flag
NO
Not flagged

Analysis Signals

Scoring Factors
Fundamental score of 50 relative to sector peers50/100
Machine learning ensemble ranks this stock at the 48th percentileP48
Blended score: 80% fundamental (50) + 20% ML (48) = 49.749.7
Risk assessment: low. Low vol 0.2%Low
Earnings quality grade D: weak earnings quality, multiple concerns. Score adjusted by 0 pointsGrade D
Conviction adj: -1.1pt (conviction=N/A)Conviction
Risk Factors
Quality concern: Negative ROIC (-16.9%) with high ROE (65.6%) โ€” capital structure distortion (possibly negative equity or one-time gain); Pipeline concentration: $1.0B biotech/pharma โ€” likely single-product revenue with binary riskFlag
Speculative: ANOMALY_MARGIN (4.0pt penalty)Speculative
Liquidity penalty: -25.0pt (grade F)Liquidity

Sector Peer Comparison(Healthcare โ€” Rank #297 of 344 stocks)

StockScoreP/ERev GrowthMarginMkt Cap
AKTS17.8N/A0.0%-2957.6%$993M
INCY89.915.821.2%25.0%$20.2B
GMAB86.113.122.8%36.4%$18.1B
CPRX83.713.723.5%37.6%$2.9B
ASND78.316.698.0%-31.7%$14.0B
EXEL78.315.17.0%33.7%$11.9B
VRTX78.232.18.9%32.9%$125.2B
NBIX75.126.521.4%16.7%$13.3B
RPRX75.025.15.1%32.4%$19.8B
HOLX74.831.11.7%13.8%$16.8B
AMGN74.226.010.0%21.0%$210.2B
ARGX73.735.178.6%38.0%$48.0B
REGN73.019.41.0%31.4%$81.3B
ALKS72.916.5-6.4%23.9%$5.0B
ISRG72.761.720.5%28.4%$177.8B
KRYS71.541.4473.0%30.7%$8.0B
Sector Average36.641.9161.5%-3292.7%โ€”

Market Sentimentvia FMP

Analyst Consensus
Buy6 analysts
Buy: 3Hold: 3
Price Target
$31consensus
Low $31Median $31High $31
+54.0% to consensus target

Company Overviewvia FMP

Aktis Oncology, Inc. operates as a clinical-stage oncology company that engages in the development of targeted radiopharmaceutical therapies for cancer treatment. The company offers a miniprotein radioconjugate platform to discover and develop radiopharmaceutical therapies that deliver the tumor-killing properties of radioisotopes. It offers Nectin-4, a miniprotein radioconjugate for the treatment of locally advanced or metastatic urothelial cancer. Its products include AKY-1189 to deliver a radioisotope to Nectin-4 expressing tumors for the treatment of metastatic urothelial cancer, breast cancer, NSCLC, colorectal cancer and cervical cancer; and AKY-2519 to deliver radioisotope to B7-H3 CD276 expressing tumors targeting prostate, lung and other solid tumors. The company was formerly known as HotKnot Therapeutics, Inc. and changed its name to Aktis Oncology, Inc. in April 2020. Aktis Oncology, Inc. was incorporated in 2020 and is based in Boston, Massachusetts.

CEO
Matthew Roden
Beta
0.00
Industry
Biotechnology

Technical Picturecomputed from daily prices

RSI (14)
59.9
Neutral
Trend
N/A
10-day vs 50-day MA
From 52W High
-31%
High: $29.16
From 52W Low
+19.8%
Low: $16.8
Moving Averages
10-Day
$18.90
Above
20-Day
$19.20
Above
50-Day
N/A
200-Day
N/A
60-Day Support
$16.8
60-Day Resistance
$29.16

Entry & Exit Zones

Avoid
No Entry
โ€”
Insufficient technical data
Exit Target
โ€”
โ€”
Stop Level
โ€”
โ€”

Not enough price history to compute reliable entry and exit zones for this stock.

Technical zones only โ€” derived from moving averages and price structure. Not financial advice. Past technical patterns do not guarantee future performance.

Financial Statementslast 4 quarters via FMP

MetricQ4 2024
Revenue$933,000
Gross Profit$933,000
Operating Income$-16M
Net Income$-12M
EPS (Diluted)$0.00
Gross Margin100.0%
Operating Margin-1675.8%
Net Margin-1292.2%

Why This Stock

Healthcare

Tradability FilterGrade F โ€” 0/100Score impact: -42.0pt

Low Tradability Warning

This stock has limited trading volume and/or float. Institutional investors may face difficulty entering or exiting positions without significant price impact. A post-hoc penalty has been applied to the composite score (this is not a backtested model factor โ€” it is a practical tradability overlay).

Volume
0
422K avg/day
Dollar Vol
0
$8M/day
Float
0
475K shares
Mkt Cap
0
$993M
Range
0
74% spread
Composite Liquidity Score0/100
FDCBA
very low float

Growth Projection Adjustment

0.7x dampening
weinstein basing

Growth estimates have been dampened based on technical and fundamental signals. This is a post-hoc adjustment to prevent overly optimistic projections for stocks showing declining momentum or deteriorating fundamentals.

Free Float
0.9%
Outstanding Shares
53M
Bid-Ask Spread
74.0%
Institutional Tradable
No

Scores are generated by a multi-stage ML pipeline combining fundamental analysis, ensemble predictions, and structural risk signals. All data is for research purposes only and does not constitute financial advice. Past performance does not guarantee future results.